Non-Crossing Deep Quantile Regression for Distributional Survival Prediction
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Abstract (arXiv)
In survival analysis the way covariates act on the risk of an event often differs between early and late failure times, yet hazard- and mean-based summaries collapse this variation into a single number. Quantile-based modeling instead describes the full conditional distribution on the original time scale, but existing censored-data methods are either inflexible or produce logically inconsistent crossing quantile curves. We propose a Censored Non-crossing Quantile (CNQ) framework for right-censored data that jointly estimates several conditional survival quantiles and guarantees valid ordering by construction, with flexibility supplied by Kolmogorov-Arnold and Transformer backbones, and we establish a finite-sample excess-risk bound holding jointly across all fitted quantile levels. Across 27 simulation settings and six cohorts the framework attains lower pinball loss than quantile-, hazard- and tree-based competitors whenever the conditional distribution is asymmetric, with interval coverage closer to nominal on all six. In two clinical case studies (METABRIC, breast cancer; FLCHAIN, population mortality) it recovers covariate effects that vary across the survival distribution and would be hidden by a single hazard ratio, and yields coherent individualized quantile milestones. Code: https://github.com/BIG-S2/deepcnq
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References · 14
- 2017Attention Is All You Needcited by 60,361
- 2024KAN: Kolmogorov-Arnold Networkscited by 649
- 2020TabTransformer: Tabular Data Modeling Using Contextual Embeddingscited by 409
- 2016DeepSurv: Personalized Treatment Recommender System Using A Cox Proportional Hazards Deep Neural Networkcited by 358
- 2019Time-to-Event Prediction with Neural Networks and Cox Regressioncited by 175
- 2021Inductive Biases and Variable Creation in Self-Attention Mechanismscited by 144
- 2023Deep Learning for Survival Analysis: A Reviewcited by 75
- 2019Continuous and Discrete-Time Survival Prediction with Neural Networkscited by 70
- 2022High-Dimensional Survival Analysis: Methods and Applicationscited by 16
- 2024An Introduction to Deep Survival Analysis Models for Predicting Time-to-Event Outcomescited by 16
- 2024Generalization Bounds and Model Complexity for Kolmogorov-Arnold Networkscited by 11
- 2022Survival Kernets: Scalable and Interpretable Deep Kernel Survival Analysis with an Accuracy Guaranteecited by 9
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