Automated generation of experimentally validated digital twins for desiccant-based low-dew-point air-conditioning systems from declarative topology specifications

In battery manufacturing, the low-dew-point air conditioning of dry rooms is among the largest energy consumers, and a physics-based digital twin offers insight for operating-point optimization beyond the installed monitoring points. Building one and calibrating it to field data each demand distinct expertise, which limits industrial uptake. We present a framework that generates a dynamic digital twin of an HVAC system from a declarative topology specification, concise enough to draft from a natural-language plant description, compiled against a purpose-built physical component library with wiring, solver, and telemetry synthesized automatically. The models carry equipment-level physics: the desiccant wheel couples heat and mass transfer through an interchangeable sorption-isotherm component, so an undisclosed commercial sorbent is calibrated as an effective isotherm rather than asserted as a material. For experimental validation we built an industrial-grade, ten-component low-dew-point system whose commercial desiccant-wheel unit holds a chamber near -40 degC frost point, and operated it in both dehumidification and bypass regimes. Generation reached a runnable model fifteen times faster than expert manual construction, and a single parameter set, fitted only to three closed-loop humidity nodes, predicts the bypass regime within 0.1 degC, the reactivation-heater power within 5%, and measured input-step responses. Identifiability analysis shows why this is prediction, not fitting: ordinary operating points constrain only one parameter combination, and the deep-dry equilibrium level of the recirculating loop supplies the missing signal. The framework shortens the path from plant description to measurement-validated twin; its criteria-based calibration is a step toward twins calibrated, not only constructed, automatically.