mlsanityData to 14 Oct 2026

Agentic evolution of physically constrained foundation models

arXiv 2606.25532 ↗First posted 24 Jun 2026cs.AI cs.AR cs.LGcited by 0

On the map: LLM agents and tool use → Web, search, and research agents

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Abstract (arXiv)

Artificial intelligence increasingly drives automated scientific discovery, yet contemporary generalist agents lack physical grounding, frequently hallucinating hardware-incompatible designs. Here, we present a physically grounded, multi-agent discovery engine that autonomously architects hardware-compliant computing systems. Anchored by an Evolutionary Knowledge Graph structuring past scientific innovations, the framework extracts an "algorithmic Chain-of-Thought" to transform blind stochastic search into directed structural evolution. Applied to the extreme testbed of foundation model deployment, the engine evolved two hardware-aware compression methodologies surpassing human-engineered heuristics: Q-Enhance mitigates long-context accuracy loss in dense models, and MoE-Salient-AQ outperforms state-of-the-art manual sparse Mixture-of-Experts designs by 3.7% at sub-3-bit regimes. Utilizing a bandwidth-efficient Sensitivity Profile, we successfully deployed a massive 235-billion-parameter model onto a constrained dual-A100 server, reducing memory requirements by 75% with a marginal 0.64% accuracy degradation. By transforming unconstrained combinatorial search into knowledge-driven autonomy, this establishes a scalable hardware-software co-design paradigm for machine-driven discovery within strict physical boundaries.

Key facts. No citing papers in the map yet (data through 14 Oct 2026). Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use. Builds on 21 of its 43 references that are in the map. First posted on arXiv 24 Jun 2026.

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21 of 43 references.

References · 21

  1. 2022GPTQ: Accurate Post-Training Quantization for Generative Pre-trained Transformerscited by 1,919
  2. 2022Competition-Level Code Generation with AlphaCodecited by 1,462
  3. 2022SmoothQuant: Accurate and Efficient Post-Training Quantization for Large Language Modelscited by 1,386
  4. 2023AWQ: Activation-aware Weight Quantization for LLM Compression and Accelerationcited by 1,298
  5. 2024QuaRot: Outlier-Free 4-Bit Inference in Rotated LLMscited by 634
  6. 2024KVQuant: Towards 10 Million Context Length LLM Inference with KV Cache Quantizationcited by 591
  7. 2023Eureka: Human-Level Reward Design via Coding Large Language Modelscited by 571
  8. 2023OmniQuant: Omnidirectionally Calibrated Quantization for Large Language Modelscited by 424
  9. 2023Atom: Low-bit Quantization for Efficient and Accurate LLM Servingcited by 272
  10. 2026Towards End-to-End Automation of AI Researchcited by 159
  11. 2020A Survey on Evolutionary Neural Architecture Searchcited by 142
  12. 2024Empowering Biomedical Discovery with AI Agentscited by 118
9 more
  1. 2024Evolutionary Computation in the Era of Large Language Model: Survey and Roadmapcited by 90
  2. 2024Evaluating Quantized Large Language Modelscited by 77
  3. 2024SliM-LLM: Salience-Driven Mixed-Precision Quantization for Large Language Modelscited by 63
  4. 2024Multi-objective Evolution of Heuristic Using Large Language Modelcited by 54
  5. 2024Autonomous LLM-driven research from data to human-verifiable research paperscited by 53
  6. 2025Jet-Nemotron: Efficient Language Model with Post Neural Architecture Searchcited by 41
  7. 2024SAC-KG: Exploiting Large Language Models as Skilled Automatic Constructors for Domain Knowledge Graphscited by 31
  8. 2025MxMoE: Mixed-precision Quantization for MoE with Accuracy and Performance Co-Designcited by 30
  9. 2024EvoPress: Accurate Dynamic Model Compression via Evolutionary Searchcited by 20

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  2. 2026CliffSearch: Structured Agentic Co-Evolution over Theory and Code for Scientific Algorithm Discovery
  3. 2025Accelerating Scientific Discovery with Autonomous Goal-evolving Agents
  4. 2026InternAgent-1.5: A Unified Agentic Framework for Long-Horizon Autonomous Scientific Discovery
  5. 2026CORAL: Towards Autonomous Multi-Agent Evolution for Open-Ended Discovery
  6. 2026GRAFT-ATHENA: Self-Improving Agentic Teams for Autonomous Discovery and Evolutionary Numerical Algorithms
  7. 2026AgentDiscover: Autonomous Discovery with Minimal Search Scaffolding
  8. 2025From AI for Science to Agentic Science: A Survey on Autonomous Scientific Discovery