LLM Doesn't Know What It Doesn't Know: Detecting Epistemic Blind Spots via Cross-Model Attribution Divergence on Clinical Tabular Data
Not on the map. Why?
Abstract (arXiv)
Large language models (LLMs) are increasingly applied to structured clinical data, yet whether they can recognize the limits of their own knowledge on such tasks remains unexplored. We study this question through the lens of cross-model attribution divergence with the goal of reducing epistemic uncertainty for structured tasks, comparing Qwen 2.5 7B and XGBoost on a prediction task via attribution divergence analysis. We report four findings. First, LLM verbalized confidence is epistemically vacuous, it outputs a near-constant (0.856-0.937) regardless of whether accuracy is 49% or 75.3%, tracking prompt format rather than prediction quality. Second, the LLM exhibits an inverse difficulty effect: accuracy drops to 64.8% when XGBoost is 99% correct, but matches XGBoost (73.8% vs. 73.1%) when it is moderately uncertain. Third, few-shot examples and SHAP-derived feature evidence are orthogonal, super-additive interventions: they reduce the Attribution Disagreement Score (ADS) from 1.54 to 0.38 and improve accuracy from 49% to 75.3% without training. Fourth, a cross-model calibrator that determined LLM reliability using attribution divergence signals reduces expected calibration error from 0.254 to 0.080, replacing uninformative verbalized confidence with patient-specific reliability estimates, without accessing model internals or requiring repeated inference. We frame these findings as a cold start problem for LLMs on structured data and outline a path toward genuine epistemic self-awareness.
Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 15 of its 24 references that are in the map. First posted on arXiv 17 Jun 2026.
Builds on
15 of 24 references.
References · 15
- 2017A Unified Approach to Interpreting Model Predictionscited by 6,555
- 2017On Calibration of Modern Neural Networkscited by 4,960
- 2022Large Language Models Encode Clinical Knowledgecited by 1,830
- 2023Can LLMs Express Their Uncertainty? An Empirical Evaluation of Confidence Elicitation in LLMscited by 974
- 2023Semantic Uncertainty: Linguistic Invariances for Uncertainty Estimation in Natural Language Generationcited by 819
- 2023Just Ask for Calibration: Strategies for Eliciting Calibrated Confidence Scores from Language Models Fine-Tuned with Human Feedbackcited by 812
- 2022Teaching Models to Express Their Uncertainty in Wordscited by 751
- 2021Tabular Data: Deep Learning is Not All You Needcited by 535
- 2022TabLLM: Few-shot Classification of Tabular Data with Large Language Modelscited by 277
- 2022The Disagreement Problem in Explainable Machine Learning: A Practitioner's Perspectivecited by 159
- 2023Large language models in healthcare and medical domain: A reviewcited by 127
- 2024Do LLMs estimate uncertainty well in instruction-following?cited by 26
Built on by
Not cited yet.