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sebis at CRF Filling 2026: A Two-Stage Local LLM Pipeline for Medical CRF Filling

arXiv 2606.13082 ↗First posted 11 Jun 2026cs.CLcited by 0

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Abstract (arXiv)

The extraction of structured clinical information from unstructured EHR notes is a persistent bottleneck in healthcare informatics. While large language models (LLMs) offer high performance, their deployment in clinical settings is hindered by privacy risks, inference costs, and the tendency to hallucinate beyond textual evidence. We address these challenges for the CL4Health 2026 Case Report Form (CRF) filling task by proposing a fully local, domain-adapted pipeline using the MedGemma-27B model. Our two-stage architecture, which separates binary presence classification from value extraction, enforces strict adherence to textual evidence and ensures deterministic outputs for negated, uncertain, or unknown states. By leveraging item-specific, few-shot in-context learning without external API calls or fine-tuning, our approach achieves a macro-F1 score of 0.55 on the official English test track. This result secures second place among all locally-hosted, open-source submissions. Our work demonstrates that privacy-preserving, on-premise LLM pipelines can achieve near-competitive performance with proprietary frontier models, providing a practical, data-sovereign framework for clinical NLP.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Builds on 3 of its 15 references that are in the map. First posted on arXiv 11 Jun 2026.

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3 of 15 references.

References · 3

  1. 2022Large Language Models are Few-Shot Clinical Information Extractorscited by 206
  2. 2025Converting Annotated Clinical Cases into Structured Case Report Formscited by 5
  3. 2026Toward Automatic Filling of Case Report Forms: A Case Study on Data from an Italian Emergency Departmentcited by 1

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