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Tabular Foundation Models for Clinical Survival Analysis via Survival-Aware Adaptation

arXiv 2606.12006 ↗First posted 10 Jun 2026cs.LG cs.AIcited by 0

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Abstract (arXiv)

Predicting time-to-event outcomes such as mortality is a fundamental task in clinical decision-making, commonly addressed through survival analysis. While classical statistical and deep learning approaches have been widely studied, they typically require task-specific training and sufficient labeled data. Recent advances in tabular foundation models offer a new paradigm by learning general-purpose representations for structured data. However, their applicability to censored time-to-event prediction in clinical settings remains underexplored, as typical applications are restricted to discrete classification rather than survival analysis tasks. In this work, we propose a lightweight adaptation approach for applying tabular foundation models to clinical survival analysis by directly training a survival-aware head on top of the pretrained representations. We study representative architectures, including TabPFN, TabDPT, and TabICL, and adapt them using a multi-task logistic regression (MTLR) head to model right-censored time-to-event outcomes. We evaluate this approach on a diverse set of public survival benchmarks and two large-scale ICU cohorts, MIMIC-IV and eICU. Our results show that this transfer learning approach achieves competitive or superior performance compared to strong baselines. On MIMIC-IV, TabDPT-FT-MTLR reaches a C-index of 0.856, corresponding to a relative improvement of +1.4% over the best non-FM baseline (DeepSurv, 0.844) and +6.7% over the best zero-shot model (0.802). On eICU, TabICL-FT-MTLR achieves 0.797, yielding gains of +1.7% (DeepSurv, 0.784) and +6.4% (0.749), respectively. These findings highlight the importance of combining pretrained tabular representations with survival-aware objectives and suggest that tabular foundation models provide a practical and effective alternative for clinical survival prediction.

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References · 7

  1. 2022TabPFN: A Transformer That Solves Small Tabular Classification Problems in a Secondcited by 674
  2. 2024TabDPT: Scaling Tabular Foundation Models on Real Datacited by 113
  3. 2019Continuous and Discrete-Time Survival Prediction with Neural Networkscited by 70
  4. 2021SurvTRACE: Transformers for Survival Analysis with Competing Eventscited by 41
  5. 2023DySurv: dynamic deep learning model for survival analysis with conditional variational inferencecited by 9
  6. 2026Tabular Foundation Models Can Do Survival Analysiscited by 9
  7. 2026Retrieval-aligned Tabular Foundation Models Enable Robust Clinical Risk Prediction in Electronic Health Records Under Real-world Constraintscited by 4

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