DualGate-Net: A Prior-Gated Dual-Encoder Framework for Histopathology Cell Detection
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Abstract (arXiv)
Cell detection in histopathology images strongly depends on surrounding tissue context, where visually similar cells may belong to different classes under different microenvironments. Recent tissue-aware methods incorporate contextual priors, but often rely on static fusion strategies that may propagate noisy information. In this work, we propose DualGate-Net, a prior-aware dual-encoder framework that combines a ConvNeXtV2-based local encoder and a SegFormer-based global encoder through a learnable prior-gated fusion mechanism. The proposed module adaptively regulates the influence of tissue priors across spatial locations, while an auxiliary foreground reconstruction branch preserves high-frequency cellular structures during training. In addition, auxiliary cellness-guided cues are incorporated to further improve localization robustness. Experiments on the OCELOT benchmark demonstrate consistent improvements, achieving macro F1-scores of 0.7722 on the validation set and 0.7345 on the test set, highlighting the effectiveness of adaptive prior integration for robust histopathology cell detection.
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References · 10
- 2021SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformerscited by 2,940
- 2023ConvNeXt V2: Co-designing and Scaling ConvNets with Masked Autoencoderscited by 712
- 2018HoVer-Net: Simultaneous Segmentation and Classification of Nuclei in Multi-Tissue Histology Imagescited by 388
- 2020PanNuke Dataset Extension, Insights and Baselinescited by 114
- 2023CellViT: Vision Transformers for Precise Cell Segmentation and Classificationcited by 108
- 2023OCELOT: Overlapped Cell on Tissue Dataset for Histopathologycited by 29
- 2021Multi-Class Cell Detection Using Spatial Context Representationcited by 24
- 2025Towards Effective and Efficient Context-aware Nucleus Detection in Histopathology Whole Slide Imagescited by 5
- 2023SoftCTM: Cell detection by soft instance segmentation and consideration of cell-tissue interactioncited by 4
- 2025ACS-SegNet: An Attention-Based CNN-SegFormer Segmentation Network for Tissue Segmentation in Histopathologycited by 4
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