Retina-RAG: Retrieval-Augmented Vision-Language Modeling for Joint Retinal Diagnosis and Clinical Report Generation
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
Diabetic Retinopathy (DR) is a leading cause of preventable blindness among working-age adults worldwide, yet most automated screening systems are limited to image-level classification and lack clinically structured reporting. We propose Retina-RAG, a low-cost modular framework that jointly performs DR severity grading, macular edema (ME) detection, and report generation. The architecture decouples a high-performance retinal classifier and a parameter-efficient vision-language model (Qwen2.5-VL-7B-Instruct) adapted via Low-Rank Adaptation (LoRA), enabling flexible component integration. A retrieval-augmented generation (RAG) module injects curated ophthalmic knowledge together with structured classifier outputs at inference time to improve diagnostic consistency and reduce hallucinations. Retina-RAG achieves an F1-score of 0.731 for DR grading and 0.948 for ME detection, substantially outperforming zero-shot Qwen (0.096, 0.732) and MMed-RAG (0.541, 0.641) on a retinal disease detection dataset with captions. For report generation, Retina-RAG attains ROUGE-L 0.438 and SBERT similarity 0.884, exceeding all baselines. The full framework operates on a single consumer-grade GPU, demonstrating that clinically structured retinal AI can be achieved with modest computational resources.
Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 18 of its 38 references that are in the map. First posted on arXiv 7 May 2026.
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18 of 38 references.
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- 2024MMed-RAG: Versatile Multimodal RAG System for Medical Vision Language Models16 Oct
- 2024RULE: Reliable Multimodal RAG for Factuality in Medical Vision Language Models6 Jul
- 2024Vision-Language Models for Medical Report Generation and Visual Question Answering: A Review4 Mar
- 2024PeFoMed: Parameter Efficient Fine-tuning of Multimodal Large Language Models for Medical Imaging5 Jan
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun
Other references · 13
- 2015Deep Residual Learning for Image Recognitioncited by 51,809
- 2022Training language models to follow instructions with human feedbackcited by 15,712
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,084
- 2021Swin Transformer: Hierarchical Vision Transformer using Shifted Windowscited by 12,082
- 2020Retrieval-Augmented Generation for Knowledge-Intensive NLP Taskscited by 9,160
- 2019Sentence-BERT: Sentence Embeddings using Siamese BERT-Networkscited by 9,049
- 2019EfficientNet: Rethinking Model Scaling for Convolutional Neural Networkscited by 6,415
- 2025Qwen2.5-VL Technical Reportcited by 5,418
- 2024Qwen2-VL: Enhancing Vision-Language Model's Perception of the World at Any Resolutioncited by 4,151
- 2023QLoRA: Efficient Finetuning of Quantized LLMscited by 3,355
- 2017Billion-scale similarity search with GPUscited by 2,477
- 2019ClinicalBERT: Modeling Clinical Notes and Predicting Hospital Readmissioncited by 487
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- 2026From Pixels to Explanations: Interpretable Diabetic Retinopathy Grading with CNN-Transformer Ensembles, Visual Explainability and Vision-Language Models
- 2024CLIP-DR: Textual Knowledge-Guided Diabetic Retinopathy Grading with Ranking-aware Prompting
- 2026FOCUS: Benchmarking Retinal Model Generalization from Foundation Vision Encoders to Multimodal LLMs
- 2025Interpretable Few-Shot Retinal Disease Diagnosis with Concept-Guided Prompting of Vision-Language Models
- 2026Benchmarking Convolutional, Transformer, Hybrid, and Vision Language Models for Multi Disease Retinal Screening
- 2023A Foundation Language-Image Model of the Retina (FLAIR): Encoding Expert Knowledge in Text Supervision
- 2025RetinalGPT: A Retinal Clinical Preference Conversational Assistant Powered by Large Vision-Language Models
- 2024RET-CLIP: A Retinal Image Foundation Model Pre-trained with Clinical Diagnostic Reports