mlsanityData to 14 Oct 2026

CBAM-Enhanced DenseNet121 for Multi-Class Chest X-Ray Classification with Grad-CAM Explainability

arXiv 2604.12305 ↗First posted 14 Apr 2026eess.IV cs.CVcited by 0

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Abstract (arXiv)

Pneumonia remains a leading cause of childhood mortality worldwide, with a heavy burden in low-resource settings such as Bangladesh where radiologist availability is limited. Most existing deep learning approaches treat pneumonia detection as a binary problem, overlooking the clinically critical distinction between bacterial and viral aetiology. This paper proposes CBAM-DenseNet121, a transfer-learning framework that integrates the Convolutional Block Attention Module (CBAM) into DenseNet121 for three-class chest X-ray classification: Normal, Bacterial Pneumonia, and Viral Pneumonia. We also conduct a systematic binary-task baseline study revealing that EfficientNetB3 (73.88%) underperforms even the custom CNN baseline (78.53%) -- a practically important negative finding for medical imaging model selection. To ensure statistical reliability, all experiments were repeated three times with independent random seeds (42, 7, 123), and results are reported as mean +/- standard deviation. CBAM-DenseNet121 achieves 84.29% +/- 1.14% test accuracy with per-class AUC scores of 0.9565 +/- 0.0010, 0.9610 +/- 0.0014, and 0.9187 +/- 0.0037 for bacterial pneumonia, normal, and viral pneumonia respectively. Grad-CAM visualizations confirm that the model attends to anatomically plausible pulmonary regions for each class, supporting interpretable deployment in resource-constrained clinical environments.

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References · 10

  1. 2015Deep Residual Learning for Image Recognitioncited by 52,096
  2. 2016Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localizationcited by 6,733
  3. 2016Densely Connected Convolutional Networkscited by 6,720
  4. 2018CBAM: Convolutional Block Attention Modulecited by 2,477
  5. 2019CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparisoncited by 1,423
  6. 2017ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseasescited by 972
  7. 2017CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learningcited by 461
  8. 2018Attention Gated Networks: Learning to Leverage Salient Regions in Medical Imagescited by 272
  9. 2017Learning to diagnose from scratch by exploiting dependencies among labelscited by 33
  10. 2016Deep image mining for diabetic retinopathy screeningcited by 25

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