Sparse Spectral LoRA: Routed Experts for Medical VLMs
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
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Abstract (arXiv)
Large vision-language models (VLMs) excel on general benchmarks but often lack robustness in medical imaging, where heterogeneous supervision induces cross-dataset interference and sensitivity to data regime (i.e., how the supervisory signals are mixed). In realistic clinical workflows, data and tasks arrive sequentially, so naive continual training further leads to catastrophic forgetting. To address these challenges, we propose MedQwen, a parameter-efficient medical VLM that couples a spectrally routed Mixture-of-Experts (MoE) with a theoretically grounded scaling rule that aligns low-rank updates with a full-rank, fully fine-tuned MoE, without changing the base architecture. Concretely, we initialize each expert from non-overlapping singular value decomposition (SVD) segments of the pretrained weight and introduce a residual compensation and scaling scheme to enable stable expert specialization and consistent routing under distribution shift. Across 23 medical datasets covering visual question answering, report generation, radiology classification, and hallucination mitigation, MedQwen achieves strong, reliable performance: it approaches full fine-tuning on zero-shot classification with 339× fewer trainable parameters, and reduces sequential forgetting to ~5% where strong baselines degrade by >20-50%.
Key facts. Cited by 1 paper in the map (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 68 of its 89 references that are in the map. First posted on arXiv 1 Apr 2026.
Builds on
68 of 89 references.
Closest ancestors · 7
Same direction, newest first
- 2025HealthGPT: A Medical Large Vision-Language Model for Unifying Comprehension and Generation via Heterogeneous Knowledge Adaptation14 Feb
- 2024UniMed-CLIP: Towards a Unified Image-Text Pretraining Paradigm for Diverse Medical Imaging Modalities13 Dec
- 2024RULE: Reliable Multimodal RAG for Factuality in Medical Vision Language Models6 Jul
- 2024D-Rax: Domain-specific Radiologic assistant leveraging multi-modal data and eXpert model predictions2 Jul
- 2024HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scale27 Jun
- 2024OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLM14 Feb
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun
Other references · 61
- 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,456
- 2016Overcoming catastrophic forgetting in neural networkscited by 4,718
- 2023Improved Baselines with Visual Instruction Tuningcited by 4,362
- 2021The Power of Scale for Parameter-Efficient Prompt Tuningcited by 3,769
- 2017Outrageously Large Neural Networks: The Sparsely-Gated Mixture-of-Experts Layercited by 3,413
- 2021Switch Transformers: Scaling to Trillion Parameter Models with Simple and Efficient Sparsitycited by 3,014
- 2019ViLBERT: Pretraining Task-Agnostic Visiolinguistic Representations for Vision-and-Language Taskscited by 2,219
- 2024Mixtral of Expertscited by 1,785
- 2023Evaluating Object Hallucination in Large Vision-Language Modelscited by 1,696
- 2019CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparisoncited by 1,410
- 2024DoRA: Weight-Decomposed Low-Rank Adaptationcited by 740
- 2019MIMIC-CXR-JPG, a large publicly available database of labeled chest radiographscited by 590
38 more
- 2022MedCLIP: Contrastive Learning from Unpaired Medical Images and Textcited by 564
- 2015Empirical Evaluation of Rectified Activations in Convolutional Networkcited by 515
- 2020PathVQA: 30000+ Questions for Medical Visual Question Answeringcited by 467
- 2024GaLore: Memory-Efficient LLM Training by Gradient Low-Rank Projectioncited by 447
- 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 444
- 2023Mitigating Hallucination in Large Multi-Modal Models via Robust Instruction Tuningcited by 439
- 2023Med-Flamingo: a Multimodal Medical Few-shot Learnercited by 387
- 2020Generating Radiology Reports via Memory-driven Transformercited by 363
- 2023AdaLoRA: Adaptive Budget Allocation for Parameter-Efficient Fine-Tuningcited by 337
- 2020CheXbert: Combining Automatic Labelers and Expert Annotations for Accurate Radiology Report Labeling Using BERTcited by 329
- 2024LoRA Learns Less and Forgets Lesscited by 313
- 2021RadGraph: Extracting Clinical Entities and Relations from Radiology Reportscited by 310
- 2024PiSSA: Principal Singular Values and Singular Vectors Adaptation of Large Language Modelscited by 261
- 2023Detecting and Preventing Hallucinations in Large Vision Language Modelscited by 254
- 2024SVD-LLM: Truncation-aware Singular Value Decomposition for Large Language Model Compressioncited by 231
- 2023PMC-CLIP: Contrastive Language-Image Pre-training using Biomedical Documentscited by 212
- 2022Language model compression with weighted low-rank factorizationcited by 192
- 2023Quilt-1M: One Million Image-Text Pairs for Histopathologycited by 192
- 2023LAMM: Language-Assisted Multi-Modal Instruction-Tuning Dataset, Framework, and Benchmarkcited by 169
- 2023ASVD: Activation-aware Singular Value Decomposition for Compressing Large Language Modelscited by 156
- 2023Pushing Mixture of Experts to the Limit: Extremely Parameter Efficient MoE for Instruction Tuningcited by 148
- 2024MixLoRA: Enhancing Large Language Models Fine-Tuning with LoRA-based Mixture of Expertscited by 144
- 2024LoRA-GA: Low-Rank Adaptation with Gradient Approximationcited by 134
- 2024HydraLoRA: An Asymmetric LoRA Architecture for Efficient Fine-Tuningcited by 118
- 2024Twin-Merging: Dynamic Integration of Modular Expertise in Model Mergingcited by 114
- 2023Mixture of Cluster-conditional LoRA Experts for Vision-language Instruction Tuningcited by 106
- 2021Medical Visual Question Answering: A Surveycited by 93
- 2024MiLoRA: Harnessing Minor Singular Components for Parameter-Efficient LLM Finetuningcited by 89
- 2024LLaVA-MoLE: Sparse Mixture of LoRA Experts for Mitigating Data Conflicts in Instruction Finetuning MLLMscited by 84
- 2023LoRAMoE: Alleviate World Knowledge Forgetting in Large Language Models via MoE-Style Plugincited by 82
- 2023VIGC: Visual Instruction Generation and Correctioncited by 80
- 2024LoRA-Pro: Are Low-Rank Adapters Properly Optimized?cited by 70
- 2024FairCLIP: Harnessing Fairness in Vision-Language Learningcited by 69
- 2024RaTEScore: A Metric for Radiology Report Generationcited by 65
- 2024MoRAL: MoE Augmented LoRA for LLMs' Lifelong Learningcited by 63
- 2024MoELoRA: Contrastive Learning Guided Mixture of Experts on Parameter-Efficient Fine-Tuning for Large Language Modelscited by 54
- 2024Upcycling Large Language Models into Mixture of Expertscited by 48
- 2023Octavius: Mitigating Task Interference in MLLMs via LoRA-MoEcited by 25
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- 2025Uncertainty-Driven Expert Control: Enhancing the Reliability of Medical Vision-Language Models
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- 2026Two-Stage Mixture-of-LoRA for Multi-Task Medical Vision-Language Learning
- 2025Adapting Foundation Vision-Language Models to Medical Diagnosis via Query-Driven Expert Bridging
- 2025Taming Vision-Language Models for Medical Image Analysis: A Comprehensive Review
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