mlsanityData to 7 Oct 2026

On the Cone Effect and Modality Gap in Medical Vision-Language Embeddings

arXiv 2603.17246 ↗First posted 18 Mar 2026cs.LGcited by 0

On the map: Multimodal LLMs / vision-language models → MLLM training and visual instruction tuning

Abstract (arXiv)

Vision-Language Models (VLMs) exhibit a characteristic "cone effect" in which nonlinear encoders map embeddings into highly concentrated regions of the representation space, contributing to cross-modal separation known as the modality gap. While this phenomenon has been widely observed, its practical impact on supervised multimodal learning -- particularly in medical domains -- remains unclear. In this work, we introduce a lightweight post-hoc mechanism that keeps pretrained VLM encoders frozen while continuously controlling cross-modal separation through a single hyperparameter λ. This enables systematic analysis of how the modality gap affects downstream multimodal performance without expensive retraining. We evaluate generalist (CLIP, SigLIP) and medically specialized (BioMedCLIP, MedSigLIP) models across diverse medical and natural datasets in a supervised multimodal settings. Results consistently show that reducing excessive modality gap improves downstream performance, with medical datasets exhibiting stronger sensitivity to gap modulation; however, fully collapsing the gap is not always optimal, and intermediate, task-dependent separation yields the best results. These findings position the modality gap as a tunable property of multimodal representations rather than a quantity that should be universally minimized.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in MLLM training and visual instruction tuning, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 17 of its 25 references that are in the map. First posted on arXiv 18 Mar 2026.

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17 of 25 references.

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  1. 2025Cross the Gap: Exposing the Intra-modal Misalignment in CLIP via Modality Inversion6 Feb

Other references · 16

  1. 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,456
  2. 2018Representation Learning with Contrastive Predictive Codingcited by 7,662
  3. 2023Sigmoid Loss for Language Image Pre-Trainingcited by 3,048
  4. 2019CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparisoncited by 1,410
  5. 2020Contrastive Learning of Medical Visual Representations from Paired Images and Textcited by 636
  6. 2022Mind the Gap: Understanding the Modality Gap in Multi-modal Contrastive Representation Learningcited by 553
  7. 2023BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairscited by 506
  8. 2025MedGemma Technical Reportcited by 398
  9. 2015Exploring Models and Data for Image Question Answeringcited by 139
  10. 2014A Multi-World Approach to Question Answering about Real-World Scenes based on Uncertain Inputcited by 112
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  12. 2019r/Fakeddit: A New Multimodal Benchmark Dataset for Fine-grained Fake News Detectioncited by 53
4 more
  1. 2023Understanding and Constructing Latent Modality Structures in Multi-modal Representation Learningcited by 53
  2. 2023ReCLIP: Refine Contrastive Language Image Pre-Training with Source Free Domain Adaptationcited by 34
  3. 2024Mitigate the Gap: Investigating Approaches for Improving Cross-Modal Alignment in CLIPcited by 23
  4. 2017Food Ingredients Recognition through Multi-label Learningcited by 6

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  1. 2025Fill the Gap: Quantifying and Reducing the Modality Gap in Image-Text Representation Learning
  2. 2026One Geometry, Different Outcomes: Readout-Dependent Effects of the Modality Gap in Vision-Language Models
  3. 2026SCALPEL: Semantic Cross-modal Alignment via LLM-Powered Encoder Learning for Medical Vision-Language Representation
  4. 2025Unified modality separation: A vision-language framework for unsupervised domain adaptation
  5. 2025Taming Vision-Language Models for Medical Image Analysis: A Comprehensive Review
  6. 2024MultiMedEval: A Benchmark and a Toolkit for Evaluating Medical Vision-Language Models
  7. 2025Beyond Cross-Modal Alignment: Measuring and Leveraging Modality Gap in Vision-Language Models
  8. 2026Enhancing Foundation VLM Robustness to Missing Modality: Scalable Diffusion for Bi-directional Feature Restoration