Testing Full Mediation of Treatment Effects and the Identifiability of Causal Mechanisms
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Abstract (arXiv)
In causal analysis, understanding the causal mechanisms through which an intervention or treatment affects an outcome is often of central interest. We propose a test to evaluate (i) whether the causal effect of a treatment that is randomly assigned conditional on covariates is fully mediated by, or operates exclusively through, observed intermediate outcomes (referred to as mediators or surrogate outcomes), and (ii) whether the various causal mechanisms operating through different mediators are identifiable conditional on covariates. We demonstrate that if both full mediation and identification of causal mechanisms hold, then the conditionally random treatment is conditionally independent of the outcome given the mediators and covariates. Furthermore, we extend our framework to settings with non-randomly assigned treatments. We show that, in this case, full mediation remains testable, while identification of causal mechanisms is no longer guaranteed. We propose a double machine learning framework for implementing the test that can incorporate high-dimensional covariates and is root-n consistent and asymptotically normal under specific regularity conditions. We also present a simulation study demonstrating good finite-sample performance of our method, along with two empirical applications revisiting randomized experiments on maternal mental health and social norms.
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References · 9
- 2013Direct and Indirect Effectscited by 280
- 2016Estimating Treatment Effects using Multiple Surrogates: The Role of the Surrogate Score and the Surrogate Indexcited by 12
- 2020Insights into the "cross-world" independence assumption of causal mediation analysiscited by 7
- 2023Doubly Robust Estimation of Direct and Indirect Quantile Treatment Effects with Machine Learningcited by 3
- 2021Contrasting Identifying Assumptions of Average Causal Effects: Robustness and Semiparametric Efficiencycited by 2
- 2025Ratio of Mediator Probability Weighting for Estimating Natural Direct and Indirect Effectscited by 2
- 2022Testing the identification of causal effects in observational datacited by 1
- 2024Testing Mechanismscited by 1
- 2024Testing identification in mediation and dynamic treatment modelscited by 1
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