NeuroWise: A Multi-Agent LLM "Glass-Box" System for Practicing Double-Empathy Communication with Autistic Partners
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Abstract (arXiv)
The double empathy problem frames communication difficulties between neurodivergent and neurotypical individuals as arising from mutual misunderstanding, yet most interventions focus on autistic individuals. We present NeuroWise, a multi-agent LLM-based coaching system that supports neurotypical users through stress visualization, interpretation of internal experiences, and contextual guidance. In a between-subjects study (N=30), NeuroWise was rated as helpful by all participants and showed a significant condition-time effect on deficit-based attributions (p=0.02): NeuroWise users reduced deficit framing, while baseline users shifted toward blaming autistic "deficits" after difficult interactions. NeuroWise users also completed conversations more efficiently (37% fewer turns, p=0.03). These findings suggest that AI-based interpretation can support attributional change by helping users recognize communication challenges as mutual.
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References · 5
- 2023Generative Agents: Interactive Simulacra of Human Behaviorcited by 3,500
- 2023AutoGen: Enabling Next-Gen LLM Applications via Multi-Agent Conversationcited by 1,906
- 2020Questioning the AI: Informing Design Practices for Explainable AI User Experiencescited by 251
- 2025ConflictLens: LLM-Based Conflict Resolution Training in Romantic Relationshipcited by 4
- 2024ASD-Chat: An Innovative Dialogue Intervention System for Children with Autism based on LLM and VB-MAPPcited by 3
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- 2026Exploring Implicit Perspectives on Autism in Large Language Models Through Multi-Agent Simulations
- 2026SocialWise: LLM-Agentic Conversation Therapy for Individuals with Autism Spectrum Disorder to Enhance Communication Skills
- 2026Algorithmic Fragility and Persona Bias in LLM-Generated Autistic Communication
- 2024Mitigating Unhelpfulness in Emotional Support Conversations with Multifaceted AI Feedback
- 2025ESC-Judge: A Framework for Comparing Emotional Support Conversational Agents
- 2026From Grasping to Speaking: Generative AI-Based Environment-Grounded VR Communication Training for Autistic Individuals ↗
- 2025Investigating AI in Peer Support via Multi-Module System-Driven Embodied Conversational Agents
- 2025WiseMind: a knowledge-guided multi-agent framework for accurate and empathetic psychiatric diagnosis