Multi-Scale Negative Coupled Information Systems (MNCIS): A Unified Spectral Topology Framework for Stability in Turbulence, AI, and Biology

Complex dynamical systems frequently encounter a recurrent structural instability: the collapse of the spectral gap, driving the system toward a low-dimensional "Zero-Mode Attractor" (e.g., spectral pile-up or over-smoothing). Building upon recent global well-posedness estimates [Hou, arXiv:2601.00638], this work generalizes the Multi-Scale Negative Coupled Information System (MNCIS) framework. We postulate that global stability requires an active topological operator - Adaptive Spectral Negative Coupling (ASNC) - functioning as a state-dependent high-pass filter that penalizes entropy accumulation at spectral boundaries. We validate this unified framework via three implementations: (1) Hydrodynamics: In 3D Navier-Stokes turbulence (N=2563), ASNC acts as a global-enstrophy adaptive sub-grid scale (SGS) model, stabilizing the inviscid limit and preserving the Kolmogorov -5/3 inertial range without artificial hyper-viscosity. Crucially, we verify that the operator remains dormant (γ ≈ 0) during the linear growth phase of physical instabilities, functioning strictly as a conditional topological clamp. (2) Artificial Intelligence: Addressing Over-smoothing in Graph Neural Networks (GNNs), we implement ASNC as a parameter-free topological constraint. Unlike baselines (e.g., DeepGCNs) relying on dense residual connections, our framework enables the training of ultra-deep 64-layer networks without residual connections, maintaining perfectly stationary feature variance (σ2 equiv 1.0) on the ogbn-arxiv benchmark. (3) Biological Physics: In reaction-diffusion morphogenesis, it stabilizes Turing patterns against diffusive washout in high-entropy regimes. Our results suggest that the MNCIS framework provides a base-independent topological condition for distinguishing viable complex systems from those collapsing into thermal equilibrium.