TraCeR: Transformer-Based Competing Risk Analysis with Longitudinal Covariates
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Abstract (arXiv)
Survival analysis is a critical tool for modeling time-to-event data. Recent deep learning-based models have reduced various modeling assumptions including proportional hazard and linearity. However, a persistent challenge remains in incorporating longitudinal covariates, with prior work largely focusing on cross-sectional features, and in assessing calibration of these models, with research primarily focusing on discrimination during evaluation. We introduce TraCeR, a transformer-based survival analysis framework for incorporating longitudinal covariates. Based on a factorized self-attention architecture, TraCeR estimates the hazard function from a sequence of measurements, naturally capturing temporal covariate interactions without assumptions about the underlying data-generating process. The framework is inherently designed to handle censored data and competing events. Experiments on multiple real-world datasets demonstrate that TraCeR achieves substantial and statistically significant performance improvements over state-of-the-art methods. Furthermore, our evaluation extends beyond discrimination metrics and assesses model calibration, addressing a key oversight in literature.
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7 of 29 references.
References · 7
- 2016Recurrent Neural Networks for Multivariate Time Series with Missing Valuescited by 554
- 2019Time-to-Event Prediction with Neural Networks and Cox Regressioncited by 175
- 2017Machine Learning for Survival Analysis: A Surveycited by 112
- 2019Recurrent Neural Networks (RNNs): A gentle Introduction and Overviewcited by 68
- 2024Toto: Time Series Optimized Transformer for Observabilitycited by 48
- 2018Deep Neural Networks for Survival Analysis Based on a Multi-Task Frameworkcited by 45
- 2021SurvTRACE: Transformers for Survival Analysis with Competing Eventscited by 41
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