Counting Clues: A Lightweight Probabilistic Baseline Can Match an LLM
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Abstract (arXiv)
Large language models (LLMs) excel on multiple-choice clinical diagnosis benchmarks, yet it is unclear how much of this performance reflects underlying probabilistic reasoning. We study this through questions from MedQA, where the task is to select the most likely diagnosis. We introduce the Frequency-Based Probabilistic Ranker (FBPR), a lightweight method that scores options with a smoothed Naive Bayes over concept-diagnosis co-occurrence statistics from a large corpus. When co-occurrence statistics were sourced from the pretraining corpora for OLMo and Llama, FBPR achieves comparable performance to the corresponding LLMs pretrained on that same corpus. Direct LLM inference and FBPR largely get different questions correct, with an overlap only slightly above random chance, indicating complementary strengths of each method. These findings highlight the continued value of explicit probabilistic baselines: they provide a meaningful performance reference point and a complementary signal for potential hybridization. While the performance of LLMs seems to be driven by a mechanism other than simple frequency aggregation, we show that an approach similar to the historically grounded, low-complexity expert systems still accounts for a substantial portion of benchmark performance.
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References · 12
- 2023Llama 2: Open Foundation and Fine-Tuned Chat Modelscited by 12,865
- 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,324
- 2023Capabilities of GPT-4 on Medical Challenge Problemscited by 630
- 2024OLMo: Accelerating the Science of Language Modelscited by 599
- 2024Dolma: an Open Corpus of Three Trillion Tokens for Language Model Pretraining Researchcited by 475
- 2024Infini-gram: Scaling Unbounded n-gram Language Models to a Trillion Tokenscited by 148
- 2025Sequential Diagnosis with Language Modelscited by 53
- 2024ClinicalBench: Can LLMs Beat Traditional ML Models in Clinical Prediction?cited by 31
- 2024What Are the Odds? Language Models Are Capable of Probabilistic Reasoningcited by 25
- 2025Extracting Probabilistic Knowledge from Large Language Models for Bayesian Network Parameterizationcited by 15
- 2024Pattern Recognition or Medical Knowledge? The Problem with Multiple-Choice Questions in Medicinecited by 13
- 2025MedPAIR: Measuring Physicians and AI Relevance Alignment in Medical Question Answeringcited by 5
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