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PC-UNet: An Enforcing Poisson Statistics U-Net for Positron Emission Tomography Denoising

arXiv 2510.14995 ↗First posted 10 Oct 2025cs.CV cs.AIcited by 0

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Abstract (arXiv)

Positron Emission Tomography (PET) is crucial in medicine, but its clinical use is limited due to high signal-to-noise ratio doses increasing radiation exposure. Lowering doses increases Poisson noise, which current denoising methods fail to handle, causing distortions and artifacts. We propose a Poisson Consistent U-Net (PC-UNet) model with a new Poisson Variance and Mean Consistency Loss (PVMC-Loss) that incorporates physical data to improve image fidelity. PVMC-Loss is statistically unbiased in variance and gradient adaptation, acting as a Generalized Method of Moments implementation, offering robustness to minor data mismatches. Tests on PET datasets show PC-UNet improves physical consistency and image fidelity, proving its ability to integrate physical information effectively.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Builds on 9 of its 27 references that are in the map. First posted on arXiv 10 Oct 2025.

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References · 9

  1. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
  2. 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,218
  3. 2018Noise2Noise: Learning Image Restoration without Clean Datacited by 526
  4. 2024VM-UNet: Vision Mamba UNet for Medical Image Segmentationcited by 286
  5. 2019Noise2Self: Blind Denoising by Self-Supervisioncited by 274
  6. 2023CoreDiff: Contextual Error-Modulated Generalized Diffusion Model for Low-Dose CT Denoising and Generalizationcited by 51
  7. 2024CSWin-UNet: Transformer UNet with Cross-Shaped Windows for Medical Image Segmentationcited by 12
  8. 2023Solving Low-Dose CT Reconstruction via GAN with Local Coherencecited by 5
  9. 2019A Novel Loss Function Incorporating Imaging Acquisition Physics for PET Attenuation Map Generation using Deep Learningcited by 4

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