Are LLM Agents the New RPA? A Comparative Study with RPA Across Enterprise Workflows

The emergence of large language models (LLMs) has introduced a new paradigm in automation: LLM agents or Agentic Automation with Computer Use (AACU). Unlike traditional Robotic Process Automation (RPA), which relies on rule-based workflows and scripting, AACU enables intelligent agents to perform tasks through natural language instructions and autonomous interaction with user interfaces. This study investigates whether AACU can serve as a viable alternative to RPA in enterprise workflow automation. We conducted controlled experiments across three standard RPA challenges data entry, monitoring, and document extraction comparing RPA (via UiPath) and AACU (via Anthropic's Computer Use Agent) in terms of speed, reliability, and development effort. Results indicate that RPA outperforms AACU in execution speed and reliability, particularly in repetitive, stable environments. However, AACU significantly reduces development time and adapts more flexibly to dynamic interfaces. While current AACU implementations are not yet production-ready, their promise in rapid prototyping and lightweight automation is evident. Future research should explore multi-agent orchestration, hybrid RPA-AACU architectures, and more robust evaluation across industries and platforms.