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DLiPath: A Benchmark for the Comprehensive Assessment of Donor Liver Based on Histopathological Image Dataset

arXiv 2506.03185 ↗First posted 30 May 2025eess.IV cs.AI cs.CVcited by 0

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Abstract (arXiv)

Pathologists comprehensive evaluation of donor liver biopsies provides crucial information for accepting or discarding potential grafts. However, rapidly and accurately obtaining these assessments intraoperatively poses a significant challenge for pathologists. Features in donor liver biopsies, such as portal tract fibrosis, total steatosis, macrovesicular steatosis, and hepatocellular ballooning are correlated with transplant outcomes, yet quantifying these indicators suffers from substantial inter- and intra-observer variability. To address this, we introduce DLiPath, the first benchmark for comprehensive donor liver assessment based on a histopathology image dataset. We collected and publicly released 636 whole slide images from 304 donor liver patients at the Department of Pathology, the Third Xiangya Hospital, with expert annotations for key pathological features (including cholestasis, portal tract fibrosis, portal inflammation, total steatosis, macrovesicular steatosis, and hepatocellular ballooning). We selected nine state-of-the-art multiple-instance learning (MIL) models based on the DLiPath dataset as baselines for extensive comparative analysis. The experimental results demonstrate that several MIL models achieve high accuracy across donor liver assessment indicators on DLiPath, charting a clear course for future automated and intelligent donor liver assessment research. Data and code are available at https://github.com/panliangrui/ACM_MM_2025.

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References · 15

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  11. 2022Transformer based multiple instance learning for weakly supervised histopathology image segmentationcited by 26
  12. 2024DGR-MIL: Exploring Diverse Global Representation in Multiple Instance Learning for Whole Slide Image Classificationcited by 25
3 more
  1. 2022Interventional Multi-Instance Learning with Deconfounded Instance-Level Predictioncited by 13
  2. 2017Label Stability in Multiple Instance Learningcited by 8
  3. 2024Feature-interactive Siamese graph encoder-based image analysis to predict STAS from histopathology images in lung cancercited by 4

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