mlsanityData to 14 Oct 2026

BehaviorSFT: Behavioral Token Conditioning for Clinical Agents Across the Proactivity Spectrum

arXiv 2505.21757 ↗First posted 27 May 2025cs.CLcited by 1

On the map: LLM agents and tool use → Medical and scientific domain agents

Abstract (arXiv)

Large Language Models (LLMs) as clinical agents require careful behavioral adaptation. While adept at reactive tasks (e.g., diagnosis reasoning), LLMs often struggle with proactive engagement, like unprompted identification of critical missing information or risks. We introduce BehaviorBench, a comprehensive dataset to evaluate agent behaviors across a clinical assistance spectrum, ranging from reactive query responses to proactive interventions (e.g., clarifying ambiguities, flagging overlooked critical data). Our BehaviorBench experiments reveal LLMs' inconsistent proactivity. To address this, we propose BehaviorSFT, a novel training strategy using behavioral tokens to explicitly condition LLMs for dynamic behavioral selection along this spectrum. BehaviorSFT boosts performance, achieving up to 97.3% overall Macro F1 on BehaviorBench and improving proactive task scores (e.g., from 95.0% to 96.5% for Qwen2.5-7B-Ins). Crucially, blind clinician evaluations confirmed BehaviorSFT-trained agents exhibit more realistic clinical behavior, striking a superior balance between helpful proactivity (e.g., timely, relevant suggestions) and necessary restraint (e.g., avoiding over-intervention) versus standard fine-tuning or explicit instructed agents.

Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 18 of its 53 references that are in the map. First posted on arXiv 27 May 2025.

Builds on

18 of 53 references.

References · 18

  1. 2023G-Eval: NLG Evaluation using GPT-4 with Better Human Alignmentcited by 2,276
  2. 2023AutoGen: Enabling Next-Gen LLM Applications via Multi-Agent Conversationcited by 1,988
  3. 2022Large Language Models Encode Clinical Knowledgecited by 1,830
  4. 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,356
  5. 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,288
  6. 2019Plug and Play Language Models: A Simple Approach to Controlled Text Generationcited by 799
  7. 2025The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Searchcited by 422
  8. 2023MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Datacited by 286
  9. 2023Think before you speak: Training Language Models With Pause Tokenscited by 264
  10. 2024Capabilities of Gemini Models in Medicinecited by 237
  11. 2022LinkBERT: Pretraining Language Models with Document Linkscited by 211
  12. 2024MediQ: Question-Asking LLMs and a Benchmark for Reliable Interactive Clinical Reasoningcited by 154
6 more
  1. 2023Clarify When Necessary: Resolving Ambiguity Through Interaction with LMscited by 98
  2. 2023Controllable Mixed-Initiative Dialogue Generation through Promptingcited by 32
  3. 2024ClinicalBench: Can LLMs Beat Traditional ML Models in Clinical Prediction?cited by 32
  4. 2025ALFA: Aligning LLMs to Ask Good Questions A Case Study in Clinical Reasoningcited by 25
  5. 2025EvalAgent: Discovering Implicit Evaluation Criteria from the Webcited by 11
  6. 2020Harnessing Uncertainty in Domain Adaptation for MRI Prostate Lesion Segmentationcited by 9

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Citing papers per year: 2025: 1.

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  1. 2026CPEMH: An Agentic Framework for Prompt-Driven Behavior Evaluation and Assurance in Foundation-Model Systems for Mental Health Screening
  2. 2026GPAgentBench-2K: Benchmarking Large Language Model Agents in Complex Clinical Action Space
  3. 2026TherapyGym: Evaluating and Aligning Clinical Fidelity and Safety in Therapy Chatbots
  4. 2025Behavior Injection: Preparing Language Models for Reinforcement Learning
  5. 2024An Active Inference Strategy for Prompting Reliable Responses from Large Language Models in Medical Practice
  6. 2025Language Agents for Hypothesis-driven Clinical Decision Making with Reinforcement Learning
  7. 2026GRASP: Gated Regression-Aware Skill Proposer for Self-Improving LLM Agents
  8. 2024AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environments