WiNGPT-3.0 Technical Report
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Abstract (arXiv)
Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy. This report focused on the development of WiNGPT-3.0, the 32-billion parameter LLMs, engineered with the objective of enhancing its capacity for medical reasoning and exploring its potential for effective integration within healthcare IT infrastructures. The broader aim is to advance towards clinically applicable models. The approach involved a multi-stage training pipeline tailored for general, medical, and clinical reasoning. This pipeline incorporated supervised fine-tuning (SFT) and reinforcement learning (RL), leveraging curated Long Chain-of-Thought (CoT) datasets, auxiliary reward models, and an evidence-based diagnostic chain simulation. WiNGPT-3.0 demonstrated strong performance: specific model variants achieved scores of 66.6 on MedCalc and 87.1 on MedQA-USMLE. Furthermore, targeted training improved performance on a clinical reasoning task from a baseline score of 58.1 to 62.5. These findings suggest that reinforcement learning, even when applied with a limited dataset of only a few thousand examples, can enhance medical reasoning accuracy. Crucially, this demonstration of RL's efficacy with limited data and computation paves the way for more trustworthy and practically deployable LLMs within clinical workflows and health information infrastructures.
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References · 8
- 2024HybridFlow: A Flexible and Efficient RLHF Frameworkcited by 2,057
- 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,356
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- 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,288
- 2022MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answeringcited by 543
- 2023CMMLU: Measuring massive multitask language understanding in Chinesecited by 449
- 2024Arcee's MergeKit: A Toolkit for Merging Large Language Modelscited by 194
- 2025Quantifying the Reasoning Abilities of LLMs on Real-world Clinical Casescited by 29
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- 2025Evaluating Computational Accuracy of Large Language Models in Numerical Reasoning Tasks for Healthcare Applications
- 2025Beyond Distillation: Pushing the Limits of Medical LLM Reasoning with Minimalist Rule-Based RL
- 2025Beyond the Leaderboard: Rethinking Medical Benchmarks for Large Language Models
- 2026Medmarks: A Comprehensive Open-Source LLM Benchmark Suite for Medical Tasks
- 2025Toward Effective Reinforcement Learning Fine-Tuning for Medical VQA in Vision-Language Models
- 2024A Preliminary Study of o1 in Medicine: Are We Closer to an AI Doctor?