Structural Entropy Guided Agent for Detecting and Repairing Knowledge Deficiencies in LLMs
On the map: LLM agents and tool use → Web, search, and research agents
Abstract (arXiv)
Large language models (LLMs) have achieved unprecedented performance by leveraging vast pretraining corpora, yet their performance remains suboptimal in knowledge-intensive domains such as medicine and scientific research, where high factual precision is required. While synthetic data provides a promising avenue for augmenting domain knowledge, existing methods frequently generate redundant samples that do not align with the model's true knowledge gaps. To overcome this limitation, we propose a novel Structural Entropy-guided Knowledge Navigator (SENATOR) framework that addresses the intrinsic knowledge deficiencies of LLMs. Our approach employs the Structure Entropy (SE) metric to quantify uncertainty along knowledge graph paths and leverages Monte Carlo Tree Search (MCTS) to selectively explore regions where the model lacks domain-specific knowledge. Guided by these insights, the framework generates targeted synthetic data for supervised fine-tuning, enabling continuous self-improvement. Experimental results on LLaMA-3 and Qwen2 across multiple domain-specific benchmarks show that SENATOR effectively detects and repairs knowledge deficiencies, achieving notable performance improvements. The code and data for our methods and experiments are available at https://github.com/weiyifan1023/senator.
Key facts. Cited by 5 papers in the map (data through 14 Oct 2026). Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use. Builds on 21 of its 57 references that are in the map. First posted on arXiv 12 May 2025.
Builds on
21 of 57 references.
References · 21
- 2024The Llama 3 Herd of Modelscited by 14,715
- 2024Qwen2.5 Technical Reportcited by 4,942
- 2022Constitutional AI: Harmlessness from AI Feedbackcited by 3,050
- 2024Qwen2 Technical Reportcited by 2,120
- 2025Does Reinforcement Learning Really Incentivize Reasoning Capacity in LLMs Beyond the Base Model?cited by 982
- 2023Baichuan 2: Open Large-scale Language Modelscited by 670
- 2023Principle-Driven Self-Alignment of Language Models from Scratch with Minimal Human Supervisioncited by 318
- 2024Quiet-STaR: Language Models Can Teach Themselves to Think Before Speakingcited by 301
- 2023MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Datacited by 286
- 2023Self-Alignment with Instruction Backtranslationcited by 151
- 2023Investigating the Factual Knowledge Boundary of Large Language Models with Retrieval Augmentationcited by 147
- 2023R-Tuning: Instructing Large Language Models to Say `I Don't Know'cited by 111
9 more
- 2023HuatuoGPT-II, One-stage Training for Medical Adaption of LLMscited by 92
- 2024Unfamiliar Finetuning Examples Control How Language Models Hallucinatecited by 87
- 2023Alignment for Honestycited by 74
- 2025Synthetic Data Generation & Multi-Step RL for Reasoning & Tool Usecited by 45
- 2024Human-Instruction-Free LLM Self-Alignment with Limited Samplescited by 25
- 2024Beyond IID: Optimizing Instruction Learning from the Perspective of Instruction Interaction and Dependencycited by 13
- 2025Discovering Knowledge Deficiencies of Language Models on Massive Knowledge Basecited by 6
- 2025SetKE: Knowledge Editing for Knowledge Elements Overlapcited by 3
- 2024Diagnosing and Remedying Knowledge Deficiencies in LLMs via Label-free Curricular Meaningful Learningcited by 2
Built on by
Citing papers per year: 2025: 1; 2026: 4.
5 papers.
- 2025AutoTIR: Autonomous Tools Integrated Reasoning via Reinforcement Learningcited by 33
- 2026Towards Compositional Generalization of LLMs via Skill Taxonomy Guided Data Synthesiscited by 4
- 2026Ontology-Constrained Neural Reasoning in Enterprise Agentic Systems: A Neurosymbolic Architecture for Domain-Grounded AI Agentscited by 3
- 2026MedCoG: Maximizing LLM Inference Density in Medical Reasoning via Meta-Cognitive Regulationcited by 2
- 2026When LLM Meets Tree Search: A Systematic View of Inference as Search in Large Language Modelscited by 0
- 2026When LLM Meets Tree Search: A Systematic View of Inference as Search in Large Language Models31 Aug 2026
- 2026Ontology-Constrained Neural Reasoning in Enterprise Agentic Systems: A Neurosymbolic Architecture for Domain-Grounded AI Agents1 Apr 2026
- 2026MedCoG: Maximizing LLM Inference Density in Medical Reasoning via Meta-Cognitive Regulation8 Feb 2026
- 2026Towards Compositional Generalization of LLMs via Skill Taxonomy Guided Data Synthesis7 Jan 2026
- 2025AutoTIR: Autonomous Tools Integrated Reasoning via Reinforcement Learning29 Jul 2025
Similar, not cited
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- 2025A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers
- 2025KnowledgeSmith: Uncovering Knowledge Updating in LLMs with Model Editing and Unlearning
- 2023Making Large Language Models Perform Better in Knowledge Graph Completion
- 2025SIGMA: Refining Large Language Model Reasoning via Sibling-Guided Monte Carlo Augmentation
- 2025Enhancing LLM Reliability via Explicit Knowledge Boundary Modeling
- 2026EDCO: Dynamic Curriculum Orchestration for Domain-specific Large Language Model Fine-tuning
- 2024Survey on Knowledge Distillation for Large Language Models: Methods, Evaluation, and Application
- 2026Probing the Knowledge Boundary: An Interactive Agentic Framework for Deep Knowledge Extraction