mlsanityData to 14 Oct 2026

Leveraging LLM Agents and Digital Twins for Fault Handling in Process Plants

arXiv 2505.02076 ↗First posted 4 May 2025cs.AI cs.MAcited by 9

On the map: LLM agents and tool use → General LLM agent frameworks and benchmarks

Abstract (arXiv)

Advances in Automation and Artificial Intelligence continue to enhance the autonomy of process plants in handling various operational scenarios. However, certain tasks, such as fault handling, remain challenging, as they rely heavily on human expertise. This highlights the need for systematic, knowledge-based methods. To address this gap, we propose a methodological framework that integrates Large Language Model (LLM) agents with a Digital Twin environment. The LLM agents continuously interpret system states and initiate control actions, including responses to unexpected faults, with the goal of returning the system to normal operation. In this context, the Digital Twin acts both as a structured repository of plant-specific engineering knowledge for agent prompting and as a simulation platform for the systematic validation and verification of the generated corrective control actions. The evaluation using a mixing module of a process plant demonstrates that the proposed framework is capable not only of autonomously controlling the mixing module, but also of generating effective corrective actions to mitigate a pipe clogging with only a few reprompts.

Key facts. Cited by 9 papers in the map (data through 14 Oct 2026). Placed in General LLM agent frameworks and benchmarks, one of 16 directions in LLM agents and tool use. Builds on 12 of its 25 references that are in the map. First posted on arXiv 4 May 2025.

Builds on

12 of 25 references.

Closest ancestors · 2

Same direction, newest first

  1. 2024Autonomous Industrial Control using an Agentic Framework with Large Language Models8 Nov
  2. 2023Towards autonomous system: flexible modular production system enhanced with large language model agents28 Apr

Other references · 10

  1. 2017Attention Is All You Needcited by 60,361
  2. 2020Retrieval-Augmented Generation for Knowledge-Intensive NLP Taskscited by 9,297
  3. 2023Sparks of Artificial General Intelligence: Early experiments with GPT-4cited by 2,592
  4. 2022Code as Policies: Language Model Programs for Embodied Controlcited by 1,210
  5. 2024Agents4PLC: Automating Closed-loop PLC Code Generation and Verification in Industrial Control Systems using LLM-based Agentscited by 26
  6. 2024LLM4PLC: Harnessing Large Language Models for Verifiable Programming of PLCs in Industrial Control Systemscited by 21
  7. 2023Pre-Trained Large Language Models for Industrial Controlcited by 16
  8. 2024Explainable Predictive Maintenance: A Survey of Current Methods, Challenges and Opportunitiescited by 10
  9. 2023Representing Timed Automata and Timing Anomalies of Cyber-Physical Production Systems in Knowledge Graphscited by 5
  10. 2024Integrating Ontology Design with the CRISP-DM in the context of Cyber-Physical Systems Maintenancecited by 4

Built on by

Cited by year (2026 to 14 Oct)

Citing papers per year: 2025: 2; 2026: 7.

9 papers.

Similar, not cited

Close in wording, no citation either way

  1. 2026Integrating Large Language Model Agents with Digital Twins for Industrial Autonomous Systems
  2. 2024Incorporating Large Language Models into Production Systems for Enhanced Task Automation and Flexibility
  3. 2025Fault2Flow: An AlphaEvolve-Optimized Human-in-the-Loop Multi-Agent System for Fault-to-Workflow Automation
  4. 2026LLM-Driven Multi-Agent Control for Skill-Based Smart Manufacturing
  5. 2026From Text to Simulation: A Multi-Agent LLM Workflow for Automated Chemical Process Design
  6. 2025Empowering Real-World: A Survey on the Technology, Practice, and Evaluation of LLM-driven Industry Agents
  7. 2024Knowledge Graph Modeling-Driven Large Language Model Operating System (LLM OS) for Task Automation in Process Engineering Problem-Solving
  8. 2026little m: An AI Agent for Industrial Process Optimization