mlsanityData to 14 Oct 2026

H2-MARL: Multi-Agent Reinforcement Learning for Pareto Optimality in Hospital Capacity Strain and Human Mobility during Epidemic

arXiv 2503.10907 ↗First posted 13 Mar 2025cs.MA cs.AI cs.CYcited by 1

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Abstract (arXiv)

The necessity of achieving an effective balance between minimizing the losses associated with restricting human mobility and ensuring hospital capacity has gained significant attention in the aftermath of COVID-19. Reinforcement learning (RL)-based strategies for human mobility management have recently advanced in addressing the dynamic evolution of cities and epidemics; however, they still face challenges in achieving coordinated control at the township level and adapting to cities of varying scales. To address the above issues, we propose a multi-agent RL approach that achieves Pareto optimality in managing hospital capacity and human mobility (H2-MARL), applicable across cities of different scales. We first develop a township-level infection model with online-updatable parameters to simulate disease transmission and construct a city-wide dynamic spatiotemporal epidemic simulator. On this basis, H2-MARL is designed to treat each division as an agent, with a trade-off dual-objective reward function formulated and an experience replay buffer enriched with expert knowledge built. To evaluate the effectiveness of the model, we construct a township-level human mobility dataset containing over one billion records from four representative cities of varying scales. Extensive experiments demonstrate that H2-MARL has the optimal dual-objective trade-off capability, which can minimize hospital capacity strain while minimizing human mobility restriction loss. Meanwhile, the applicability of the proposed model to epidemic control in cities of varying scales is verified, which showcases its feasibility and versatility in practical applications.

Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Builds on 9 of its 90 references that are in the map. First posted on arXiv 13 Mar 2025.

Builds on

9 of 90 references.

References · 9

  1. 2024A Review of Graph Neural Networks in Epidemic Modelingcited by 31
  2. 2020COVID-ABS: An Agent-Based Model of COVID-19 Epidemic to Simulate Health and Economic Effects of Social Distancing Interventionscited by 18
  3. 2020Reinforced Epidemic Control: Saving Both Lives and Economycited by 9
  4. 2022Exploring the Pareto front of multi-objective COVID-19 mitigation policies using reinforcement learningcited by 9
  5. 2020Multi-Objective Model-based Reinforcement Learning for Infectious Disease Controlcited by 7
  6. 2023Predicting COVID-19 pandemic by spatio-temporal graph neural networks: A New Zealand's studycited by 6
  7. 2023MSGNN: Multi-scale Spatio-temporal Graph Neural Network for Epidemic Forecastingcited by 6
  8. 2023Adaptive Multi-Agent Deep Reinforcement Learning for Timely Healthcare Interventionscited by 3
  9. 2024Modeling and Optimization of Epidemiological Control Policies Through Reinforcement Learningcited by 1

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  1. 2025Learning Pareto-Optimal Pandemic Intervention Policies with MORL
  2. 2025Optimization of Infectious Disease Intervention Measures Based on Reinforcement Learning -- Empirical analysis based on UK COVID-19 epidemic data
  3. 2025On a Reinforcement Learning Methodology for Epidemic Control, with application to COVID-19
  4. 2024SIR-RL: Reinforcement Learning for Optimized Policy Control during Epidemiological Outbreaks in Emerging Market and Developing Economies
  5. 2026Optimizing Resource-Constrained Non-Pharmaceutical Interventions for Multi-Cluster Outbreak Control Using Hierarchical Reinforcement Learning
  6. 2024Advancing Multi-Organ Disease Care: A Hierarchical Multi-Agent Reinforcement Learning Framework
  7. 2025Reward Engineering for Spatial Epidemic Simulations: A Reinforcement Learning Platform for Individual Behavioral Learning
  8. 2024Spatio-Temporal SIR Model of Pandemic Spread During Warfare with Optimal Dual-use Healthcare System Administration using Deep Reinforcement Learning