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Clinical Trials Ontology Engineering with Large Language Models

arXiv 2412.14387 ↗First posted 18 Dec 2024cs.AIcited by 0

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Abstract (arXiv)

Managing clinical trial information is currently a significant challenge for the medical industry, as traditional methods are both time-consuming and costly. This paper proposes a simple yet effective methodology to extract and integrate clinical trial data in a cost-effective and time-efficient manner. Allowing the medical industry to stay up-to-date with medical developments. Comparing time, cost, and quality of the ontologies created by humans, GPT3.5, GPT4, and Llama3 (8b & 70b). Findings suggest that large language models (LLM) are a viable option to automate this process both from a cost and time perspective. This study underscores significant implications for medical research where real-time data integration from clinical trials could become the norm.

Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 8 of its 29 references that are in the map. First posted on arXiv 18 Dec 2024.

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References · 8

  1. 2017Attention Is All You Needcited by 60,361
  2. 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,399
  3. 2020Language Models are Few-Shot Learnerscited by 32,419
  4. 2023LLaMA: Open and Efficient Foundation Language Modelscited by 14,132
  5. 2020Med-BERT: pre-trained contextualized embeddings on large-scale structured electronic health records for disease predictioncited by 373
  6. 2023Do We Still Need Clinical Language Models?cited by 98
  7. 2019End-to-end Named Entity Recognition and Relation Extraction using Pre-trained Language Modelscited by 11
  8. 2018OK Google, What Is Your Ontology? Or: Exploring Freebase Classification to Understand Google's Knowledge Graphcited by 5

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