mlsanityData to 13 Oct 2026

Enhancing In-Hospital Mortality Prediction Using Multi-Representational Learning with LLM-Generated Expert Summaries

arXiv 2411.16818 ↗First posted 25 Nov 2024cs.CL cs.AI cs.LGcited by 2

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Abstract (arXiv)

To evaluate a multi-representational framework in which large language model (LLM)-generated expert summaries of intensive care unit (ICU) notes are fused with physiology for in-hospital mortality (IHM) prediction, and to determine how much of the resulting gain is non-redundant with the notes themselves. Using MIMIC-III (19,211 first ICU stays, 12.83% mortality), we encoded 48-hour physiology, clinical notes, and LLM summaries generated under a prompt forbidding prognostication, then fused them. Redundancy was assessed by ridge recoverability, linear probes, and retrained ablations substituting a note-orthogonal residual or a patient-shuffled summary embedding. On 3,843 held-out stays, fusion reached AUPRC 0.4977/AUROC 0.8429 versus 0.3625/0.7770 for physiology alone. Ridge regression from note embeddings explained 40.8% of summary-embedding variance. The note-orthogonal residual retained a minority of the gain (+0.0258 AUPRC, 95% CI 0.005--0.047; 28%), while patient-shuffled summaries fell below the reference. Summaries improve prediction patient-specifically, but predominantly by reorganizing information the notes already contain.

Key facts. Cited by 2 papers in the map (data through 13 Oct 2026). Builds on 6 of its 10 references that are in the map. First posted on arXiv 25 Nov 2024.

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6 of 10 references.

References · 6

  1. 2021On the Opportunities and Risks of Foundation Modelscited by 3,999
  2. 2019BioBERT: a pre-trained biomedical language representation model for biomedical text miningcited by 1,942
  3. 2019Publicly Available Clinical BERT Embeddingscited by 999
  4. 2023Just Ask for Calibration: Strategies for Eliciting Calibrated Confidence Scores from Language Models Fine-Tuned with Human Feedbackcited by 800
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  6. 2018Learning Tasks for Multitask Learning: Heterogenous Patient Populations in the ICUcited by 21

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Citing papers per year: 2025: 1; 2026: 1.

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  1. 2026Standalone LLM and a Pre-specified Agentic Pipeline for Explaining ICU Mortality Predictions: a Feasibility Study on the eICU Demo Dataset
  2. 2026Rethinking Large Language Models For Irregular Time Series Classification In Critical Care
  3. 2026Towards Multidisciplinary Summarization of Hospital Stays: Efficient Sentence-Level Clinical Provenance Categorization
  4. 2024Harmonising the Clinical Melody: Tuning Large Language Models for Hospital Course Summarisation in Clinical Coding
  5. 2026Large Language Models as Unified Multimodal Learners for Clinical Prediction
  6. 2026LLM4EHR: Aligning Clinical Time Series with Medical Event Sequences via Large Language Models
  7. 2026A Multimodal Deep Learning Framework for Predicting ICU Deterioration: Integrating ECG Waveforms with Clinical Data and Clinician Benchmarking
  8. 2024Large Language Model Capabilities in Perioperative Risk Prediction and Prognostication