Investigating the Role of Prompting and External Tools in Hallucination Rates of Large Language Models
On the map: LLM agents and tool use → Medical and scientific domain agents
Abstract (arXiv)
Large Language Models (LLMs) are powerful computational models trained on extensive corpora of human-readable text, enabling them to perform general-purpose language understanding and generation. LLMs have garnered significant attention in both industry and academia due to their exceptional performance across various natural language processing (NLP) tasks. Despite these successes, LLMs often produce inaccuracies, commonly referred to as hallucinations. Prompt engineering, the process of designing and formulating instructions for LLMs to perform specific tasks, has emerged as a key approach to mitigating hallucinations. This paper provides a comprehensive empirical evaluation of different prompting strategies and frameworks aimed at reducing hallucinations in LLMs. Various prompting techniques are applied to a broad set of benchmark datasets to assess the accuracy and hallucination rate of each method. Additionally, the paper investigates the influence of tool-calling agents (LLMs augmented with external tools to enhance their capabilities beyond language generation) on hallucination rates in the same benchmarks. The findings demonstrate that the optimal prompting technique depends on the type of problem, and that simpler techniques often outperform more complex methods in reducing hallucinations. Furthermore, it is shown that LLM agents can exhibit significantly higher hallucination rates due to the added complexity of external tool usage.
Key facts. Cited by 4 papers in the map (data through 7 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 6 of its 19 references that are in the map. First posted on arXiv 25 Oct 2024.
Builds on
6 of 19 references.
References · 6
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- 2020Measuring Massive Multitask Language Understandingcited by 7,768
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- 2023Improving Factuality and Reasoning in Language Models through Multiagent Debatecited by 1,739
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Built on by
Citing papers per year: 2025: 2; 2026: 2.
4 papers.
- 2025Combinatorial Optimization for All: Using LLMs to Aid Non-Experts in Improving Optimization Algorithmscited by 5
- 2025FasterPy: An LLM-based Code Execution Efficiency Optimization Frameworkcited by 3
- 2026Mitigating LLM Hallucinations through Domain-Grounded Tiered Retrievalcited by 0
- 2026Hallucinations in LLMs: A Lifecycle-Based Survey of Causes, Detection, Mitigation, and Preventioncited by 0
- 2026Hallucinations in LLMs: A Lifecycle-Based Survey of Causes, Detection, Mitigation, and Prevention20 Jul 2026
- 2026Mitigating LLM Hallucinations through Domain-Grounded Tiered Retrieval18 Mar 2026
- 2025FasterPy: An LLM-based Code Execution Efficiency Optimization Framework28 Dec 2025
- 2025Combinatorial Optimization for All: Using LLMs to Aid Non-Experts in Improving Optimization Algorithms14 Mar 2025
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- 2025Triggering Hallucinations in LLMs: A Quantitative Study of Prompt-Induced Hallucination in Large Language Models
- 2024A Comprehensive Survey of Hallucination Mitigation Techniques in Large Language Models
- 2026Evaluating Hallucinations in Domain-Adapted Large Language Models
- 2025LLM-based Agents Suffer from Hallucinations: A Survey of Taxonomy, Methods, and Directions
- 2025From "Hallucination" to "Suture": Insights from Language Philosophy to Enhance Large Language Models
- 2024Banishing LLM Hallucinations Requires Rethinking Generalization
- 2026Mitigating Prompt-Induced Hallucinations in Large Language Models via Structured Reasoning
- 2023A Survey on Hallucination in Large Language Models: Principles, Taxonomy, Challenges, and Open Questions