A Knowledge-Enhanced Disease Diagnosis Method Based on Prompt Learning and BERT Integration
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Abstract (arXiv)
This paper proposes a knowledge-enhanced disease diagnosis method based on a prompt learning framework. The method retrieves structured knowledge from external knowledge graphs related to clinical cases, encodes it, and injects it into the prompt templates to enhance the language model's understanding and reasoning capabilities for the task.We conducted experiments on three public datasets: CHIP-CTC, IMCS-V2-NER, and KUAKE-QTR. The results show that the proposed method significantly outperforms existing models across multiple evaluation metrics, with an F1 score improvement of 2.4% on the CHIP-CTC dataset, 3.1% on the IMCS-V2-NER dataset,and 4.2% on the KUAKE-QTR dataset. Additionally,ablation studies confirmed the critical role of the knowledge injection module,as the removal of this module resulted in a significant drop in F1 score. The experimental results demonstrate that the proposed method not only effectively improves the accuracy of disease diagnosis but also enhances the interpretability of the predictions, providing more reliable support and evidence for clinical diagnosis.
Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Builds on 5 of its 29 references that are in the map. First posted on arXiv 16 Sep 2024.
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References · 5
- 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,399
- 2019Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformercited by 14,599
- 2014Neural Machine Translation by Jointly Learning to Align and Translatecited by 4,548
- 2019BioBERT: a pre-trained biomedical language representation model for biomedical text miningcited by 1,947
- 2023An Analysis on Large Language Models in Healthcare: A Case Study of BioBERTcited by 3
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- 2025BiomedXPro: Prompt Optimization for Explainable Diagnosis with Biomedical Vision Language Models
- 2026MultiDx: A Multi-Source Knowledge Integration Framework towards Diagnostic Reasoning
- 2026EviCare: Enhancing Diagnosis Prediction with Deep Model-Guided Evidence for In-Context Reasoning
- 2025RAD: Towards Trustworthy Retrieval-Augmented Multi-modal Clinical Diagnosis
- 2025KERAP: A Knowledge-Enhanced Reasoning Approach for Accurate Zero-shot Diagnosis Prediction Using Multi-agent LLMs