Wound Tissue Segmentation in Diabetic Foot Ulcer Images Using Deep Learning: A Pilot Study
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Abstract (arXiv)
Identifying individual tissues, so-called tissue segmentation, in diabetic foot ulcer (DFU) images is a challenging task and little work has been published, largely due to the limited availability of a clinical image dataset. To address this gap, we have created a DFUTissue dataset for the research community to evaluate wound tissue segmentation algorithms. The dataset contains 110 images with tissues labeled by wound experts and 600 unlabeled images. Additionally, we conducted a pilot study on segmenting wound characteristics including fibrin, granulation, and callus using deep learning. Due to the limited amount of annotated data, our framework consists of both supervised learning (SL) and semi-supervised learning (SSL) phases. In the SL phase, we propose a hybrid model featuring a Mix Transformer (MiT-b3) in the encoder and a CNN in the decoder, enhanced by the integration of a parallel spatial and channel squeeze-and-excitation (P-scSE) module known for its efficacy in improving boundary accuracy. The SSL phase employs a pseudo-labeling-based approach, iteratively identifying and incorporating valuable unlabeled images to enhance overall segmentation performance. Comparative evaluations with state-of-the-art methods are conducted for both SL and SSL phases. The SL achieves a Dice Similarity Coefficient (DSC) of 84.89%, which has been improved to 87.64% in the SSL phase. Furthermore, the results are benchmarked against two widely used SSL approaches: Generative Adversarial Networks and Cross-Consistency Training. Additionally, our hybrid model outperforms the state-of-the-art methods with a 92.99% DSC in performing binary segmentation of DFU wound areas when tested on the Chronic Wound dataset. Codes and data are available at https://github.com/uwm-bigdata/DFUTissueSegNet.
Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Builds on 25 of its 50 references that are in the map. First posted on arXiv 23 Jun 2024.
Builds on
25 of 50 references.
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13 more
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Built on by
Citing papers per year: 2025: 2; 2026: 3.
5 papers.
- 2025TransUNet-GradCAM: A Hybrid Transformer-U-Net with Self-Attention and Explainable Visualizations for Foot Ulcer Segmentationcited by 2
- 2025Beyond Labels: Zero-Shot Diabetic Foot Ulcer Wound Segmentation with Self-attention Diffusion Models and the Potential for Text-Guided Customizationcited by 1
- 2026Automated multi-class wound assessment using dedicated instance segmentation models for boundary detection and classificationcited by 0
- 2026WoundFormer: Multi-Scale Spatial Feature Fusion for Multi-Class Wound Tissue Segmentationcited by 0
- 2026LUTSeg: A Longitudinal Multi-Expert Dataset for Ulcer Tissue Segmentationcited by 0
- 2026LUTSeg: A Longitudinal Multi-Expert Dataset for Ulcer Tissue Segmentation26 Aug 2026
- 2026WoundFormer: Multi-Scale Spatial Feature Fusion for Multi-Class Wound Tissue Segmentation19 May 2026
- 2026Automated multi-class wound assessment using dedicated instance segmentation models for boundary detection and classification28 Mar 2026
- 2025TransUNet-GradCAM: A Hybrid Transformer-U-Net with Self-Attention and Explainable Visualizations for Foot Ulcer Segmentation4 Aug 2025
- 2025Beyond Labels: Zero-Shot Diabetic Foot Ulcer Wound Segmentation with Self-attention Diffusion Models and the Potential for Text-Guided Customization24 Apr 2025