PPINtonus: Early Detection of Parkinson's Disease Using Deep-Learning Tonal Analysis

PPINtonus is a system for the early detection of Parkinson's Disease (PD) utilizing deep-learning tonal analysis, providing a cost-effective and accessible alternative to traditional neurological examinations. Partnering with the Parkinson's Voice Project (PVP), PPINtonus employs a semi-supervised conditional generative adversarial network to generate synthetic data points, enhancing the training dataset for a multi-layered deep neural network. Combined with PRAAT phonetics software, this network accurately assesses biomedical voice measurement values from a simple 120-second vocal test performed with a standard microphone in typical household noise conditions. The model's performance was validated using a confusion matrix, achieving an impressive 92.5 % accuracy with a low false negative rate. PPINtonus demonstrated a precision of 92.7 %, making it a reliable tool for early PD detection. The non-intrusive and efficient methodology of PPINtonus can significantly benefit developing countries by enabling early diagnosis and improving the quality of life for millions of PD patients through timely intervention and management.