Qibo: A Large Language Model for Traditional Chinese Medicine
Not on the map. Why?
Abstract (arXiv)
Large Language Models (LLMs) has made significant progress in a number of professional fields, including medicine, law, and finance. However, in traditional Chinese medicine (TCM), there are challenges such as the essential differences between theory and modern medicine, the lack of specialized corpus resources, and the fact that relying only on supervised fine-tuning may lead to overconfident predictions. To address these challenges, we propose a two-stage training approach that combines continuous pre-training and supervised fine-tuning. A notable contribution of our study is the processing of a 2GB corpus dedicated to TCM, constructing pre-training and instruction fine-tuning datasets for TCM, respectively. In addition, we have developed Qibo-Benchmark, a tool that evaluates the performance of LLM in the TCM on multiple dimensions, including subjective, objective, and three TCM NLP tasks. The medical LLM trained with our pipeline, named Qibo, exhibits significant performance boosts. Compared to the baselines, the average subjective win rate is 63%, the average objective accuracy improved by 23% to 58%, and the Rouge-L scores for the three TCM NLP tasks are 0.72, 0.61, and 0.55. Finally, we propose a pipline to apply Qibo to TCM consultation and demonstrate the model performance through the case study.
Key facts. Cited by 13 papers in the map (data through 14 Oct 2026). Builds on 26 of its 51 references that are in the map. First posted on arXiv 24 Mar 2024.
Builds on
26 of 51 references.
References · 26
- 2023GPT-4 Technical Reportcited by 18,396
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,380
- 2023LLaMA: Open and Efficient Foundation Language Modelscited by 14,132
- 2023Qwen Technical Reportcited by 3,344
- 2022Self-Instruct: Aligning Language Models with Self-Generated Instructionscited by 2,724
- 2022BLOOM: A 176B-Parameter Open-Access Multilingual Language Modelcited by 1,984
- 2022Large Language Models Encode Clinical Knowledgecited by 1,830
- 2021Multitask Prompted Training Enables Zero-Shot Task Generalizationcited by 1,470
- 2019ZeRO: Memory Optimizations Toward Training Trillion Parameter Modelscited by 1,301
- 2023LIMA: Less Is More for Alignmentcited by 1,100
- 2021GLM: General Language Model Pretraining with Autoregressive Blank Infillingcited by 1,031
- 2023Baichuan 2: Open Large-scale Language Modelscited by 670
14 more
- 2023An Empirical Study of Catastrophic Forgetting in Large Language Models During Continual Fine-tuningcited by 639
- 2016SeqGAN: Sequence Generative Adversarial Nets with Policy Gradientcited by 376
- 2021Pre-Trained Models: Past, Present and Futurecited by 319
- 2023Principle-Driven Self-Alignment of Language Models from Scratch with Minimal Human Supervisioncited by 318
- 2023Efficient and Effective Text Encoding for Chinese LLaMA and Alpacacited by 305
- 2023MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Datacited by 286
- 2023The False Promise of Imitating Proprietary LLMscited by 263
- 2022Is Reinforcement Learning (Not) for Natural Language Processing: Benchmarks, Baselines, and Building Blocks for Natural Language Policy Optimizationcited by 246
- 2023HuatuoGPT, towards Taming Language Model to Be a Doctorcited by 214
- 2021Muppet: Massive Multi-task Representations with Pre-Finetuningcited by 192
- 2023DoctorGLM: Fine-tuning your Chinese Doctor is not a Herculean Taskcited by 131
- 2023Zhongjing: Enhancing the Chinese Medical Capabilities of Large Language Model through Expert Feedback and Real-world Multi-turn Dialoguecited by 119
- 2022Fengshenbang 1.0: Being the Foundation of Chinese Cognitive Intelligencecited by 70
- 2023Huatuo-26M, a Large-scale Chinese Medical QA Datasetcited by 46
Built on by
Citing papers per year: 2024: 3; 2025: 5; 2026: 5.
13 papers.
Sort:
By area:
- 2024A Survey on Large Language Models from General Purpose to Medical Applications: Datasets, Methodologies, and Evaluationscited by 16
- 2024BianCang: A Traditional Chinese Medicine Large Language Modelcited by 12
- 2025OpenTCM: A GraphRAG-Empowered LLM-based System for Traditional Chinese Medicine Knowledge Retrieval and Diagnosiscited by 10
- 2025MTCMB: A Multi-Task Benchmark Framework for Evaluating LLMs on Knowledge, Reasoning, and Safety in Traditional Chinese Medicinecited by 4
- 2024Traditional Chinese Medicine Case Analysis System for High-Level Semantic Abstraction: Optimized with Prompt and RAGcited by 1
- 2025Improving TCM Question Answering through Tree-Organized Self-Reflective Retrieval with LLMscited by 1
- 2025DoPI: Doctor-like Proactive Interrogation LLM for Traditional Chinese Medicinecited by 1
- 2026VerifAI: A Verifiable Open-Source Search Engine for Biomedical Question Answeringcited by 1
- 2025RACE-Align: Retrieval-Augmented and Chain-of-Thought Enhanced Preference Alignment for Large Language Modelscited by 0
- 2026TCM-DiffRAG: Personalized Syndrome Differentiation Reasoning Method for Traditional Chinese Medicine based on Knowledge Graph and Chain of Thoughtcited by 0
- 2026DongYuan: An LLM-Based Framework for Integrative Chinese and Western Medicine Spleen-Stomach Disorders Diagnosiscited by 0
- 2026TCMaster: Confidence-Aware Querying and Workload-Guided Physical Design for Multi-Source Traditional Chinese Medicine Knowledge Graphscited by 0
- 2026Output Discipline Sets the Floor: A Falsification-Guided, Model-Agnostic Agent Protocol for Auditable Hypothesis-Driven Decision Making13 Oct 2026
- 2026TCMaster: Confidence-Aware Querying and Workload-Guided Physical Design for Multi-Source Traditional Chinese Medicine Knowledge Graphs22 Sep 2026
- 2026DongYuan: An LLM-Based Framework for Integrative Chinese and Western Medicine Spleen-Stomach Disorders Diagnosis30 Mar 2026
- 2026TCM-DiffRAG: Personalized Syndrome Differentiation Reasoning Method for Traditional Chinese Medicine based on Knowledge Graph and Chain of Thought26 Feb 2026
- 2026VerifAI: A Verifiable Open-Source Search Engine for Biomedical Question Answering16 Jan 2026
- 2025DoPI: Doctor-like Proactive Interrogation LLM for Traditional Chinese Medicine7 Jul 2025
- 2025RACE-Align: Retrieval-Augmented and Chain-of-Thought Enhanced Preference Alignment for Large Language Models3 Jun 2025
- 2025MTCMB: A Multi-Task Benchmark Framework for Evaluating LLMs on Knowledge, Reasoning, and Safety in Traditional Chinese Medicine2 Jun 2025
- 2025OpenTCM: A GraphRAG-Empowered LLM-based System for Traditional Chinese Medicine Knowledge Retrieval and Diagnosis28 Apr 2025
- 2025Improving TCM Question Answering through Tree-Organized Self-Reflective Retrieval with LLMs13 Feb 2025
- 2024Traditional Chinese Medicine Case Analysis System for High-Level Semantic Abstraction: Optimized with Prompt and RAG23 Nov 2024
- 2024BianCang: A Traditional Chinese Medicine Large Language Model17 Nov 2024
- 2025MTCMB: A Multi-Task Benchmark Framework for Evaluating LLMs on Knowledge, Reasoning, and Safety in Traditional Chinese Medicinecited by 4
- 2025RACE-Align: Retrieval-Augmented and Chain-of-Thought Enhanced Preference Alignment for Large Language Modelscited by 0
- 2026TCM-DiffRAG: Personalized Syndrome Differentiation Reasoning Method for Traditional Chinese Medicine based on Knowledge Graph and Chain of Thoughtcited by 0
- 2026TCM-DiffRAG: Personalized Syndrome Differentiation Reasoning Method for Traditional Chinese Medicine based on Knowledge Graph and Chain of Thought26 Feb 2026
- 2025RACE-Align: Retrieval-Augmented and Chain-of-Thought Enhanced Preference Alignment for Large Language Models3 Jun 2025
- 2025MTCMB: A Multi-Task Benchmark Framework for Evaluating LLMs on Knowledge, Reasoning, and Safety in Traditional Chinese Medicine2 Jun 2025
- 2024A Survey on Large Language Models from General Purpose to Medical Applications: Datasets, Methodologies, and Evaluationscited by 16
- 2024BianCang: A Traditional Chinese Medicine Large Language Modelcited by 12
- 2025OpenTCM: A GraphRAG-Empowered LLM-based System for Traditional Chinese Medicine Knowledge Retrieval and Diagnosiscited by 10
- 2024Traditional Chinese Medicine Case Analysis System for High-Level Semantic Abstraction: Optimized with Prompt and RAGcited by 1
- 2025Improving TCM Question Answering through Tree-Organized Self-Reflective Retrieval with LLMscited by 1
- 2025DoPI: Doctor-like Proactive Interrogation LLM for Traditional Chinese Medicinecited by 1
- 2026DongYuan: An LLM-Based Framework for Integrative Chinese and Western Medicine Spleen-Stomach Disorders Diagnosiscited by 0
- 2026TCMaster: Confidence-Aware Querying and Workload-Guided Physical Design for Multi-Source Traditional Chinese Medicine Knowledge Graphscited by 0
- 2026TCMaster: Confidence-Aware Querying and Workload-Guided Physical Design for Multi-Source Traditional Chinese Medicine Knowledge Graphs22 Sep 2026
- 2026DongYuan: An LLM-Based Framework for Integrative Chinese and Western Medicine Spleen-Stomach Disorders Diagnosis30 Mar 2026
- 2025DoPI: Doctor-like Proactive Interrogation LLM for Traditional Chinese Medicine7 Jul 2025
- 2025OpenTCM: A GraphRAG-Empowered LLM-based System for Traditional Chinese Medicine Knowledge Retrieval and Diagnosis28 Apr 2025
- 2025Improving TCM Question Answering through Tree-Organized Self-Reflective Retrieval with LLMs13 Feb 2025
- 2024Traditional Chinese Medicine Case Analysis System for High-Level Semantic Abstraction: Optimized with Prompt and RAG23 Nov 2024
- 2024BianCang: A Traditional Chinese Medicine Large Language Model17 Nov 2024
- 2024A Survey on Large Language Models from General Purpose to Medical Applications: Datasets, Methodologies, and Evaluations14 Jun 2024