mlsanityData to 7 Oct 2026

A Spectrum Evaluation Benchmark for Medical Multi-Modal Large Language Models

arXiv 2402.11217 ↗First posted 17 Feb 2024cs.CL cs.CVcited by 16

On the map: Multimodal LLMs / vision-language models → Medical vision-language models

Abstract (arXiv)

The significant breakthroughs of Medical Multi-Modal Large Language Models (Med-MLLMs) renovate modern healthcare with robust information synthesis and medical decision support. However, these models are often evaluated on benchmarks that are unsuitable for the Med-MLLMs due to the complexity of real-world diagnostics across diverse specialties. To address this gap, we introduce Asclepius, a novel Med-MLLM benchmark that comprehensively assesses Med-MLLMs in terms of: distinct medical specialties (cardiovascular, gastroenterology, etc.) and different diagnostic capacities (perception, disease analysis, etc.). Grounded in 3 proposed core principles, Asclepius ensures a comprehensive evaluation by encompassing 15 medical specialties, stratifying into 3 main categories and 8 sub-categories of clinical tasks, and exempting overlap with existing VQA dataset. We further provide an in-depth analysis of 6 Med-MLLMs and compare them with 3 human specialists, providing insights into their competencies and limitations in various medical contexts. Our work not only advances the understanding of Med-MLLMs' capabilities but also sets a precedent for future evaluations and the safe deployment of these models in clinical environments.

Key facts. Cited by 16 papers in the map (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 17 of its 56 references that are in the map. First posted on arXiv 17 Feb 2024.

Builds on

17 of 56 references.

Closest ancestors · 4

Same direction, newest first

  1. 2024OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLM14 Feb
  2. 2023Multimodal LLMs for health grounded in individual-specific data18 Jul
  3. 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun
  4. 2023BiomedGPT: A Generalist Vision-Language Foundation Model for Diverse Biomedical Tasks26 May

Other references · 13

  1. 2019CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparisoncited by 1,410
  2. 2021MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classificationcited by 682
  3. 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 444
  4. 2023Med-Flamingo: a Multimodal Medical Few-shot Learnercited by 387
  5. 2022Data Contamination: From Memorization to Exploitationcited by 234
  6. 2023PMC-CLIP: Contrastive Language-Image Pre-training using Biomedical Documentscited by 212
  7. 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Datacited by 176
  8. 2024A Vision-Language Foundation Model to Enhance Efficiency of Chest X-ray Interpretationcited by 79
  9. 2023Can GPT-4V(ision) Serve Medical Applications? Case Studies on GPT-4V for Multimodal Medical Diagnosiscited by 77
  10. 2020MedICaT: A Dataset of Medical Images, Captions, and Textual Referencescited by 71
  11. 2022Long-Tailed Classification of Thorax Diseases on Chest X-Ray: A New Benchmark Studycited by 45
  12. 2023A Systematic Evaluation of GPT-4V's Multimodal Capability for Medical Image Analysiscited by 37
1 more
  1. 2018The HAM10000 dataset, a large collection of multi-source dermatoscopic images of common pigmented skin lesionscited by 26

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2024: 9; 2025: 6; 2026: 1.

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  1. 2024A Survey on Benchmarks of Multimodal Large Language Modelscited by 81
  2. 2024CARES: A Comprehensive Benchmark of Trustworthiness in Medical Vision Language Modelscited by 64
  3. 2024A Survey on Evaluation of Multimodal Large Language Modelscited by 46
  4. 2024MMAD: A Comprehensive Benchmark for Multimodal Large Language Models in Industrial Anomaly Detectioncited by 46
  5. 2025A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontierscited by 34
  6. 2024A Survey on Multimodal Benchmarks: In the Era of Large AI Modelscited by 27
  7. 2024MediConfusion: Can you trust your AI radiologist? Probing the reliability of multimodal medical foundation modelscited by 22
  8. 2024Medchain: Bridging the Gap Between LLM Agents and Clinical Practice with Interactive Sequencecited by 15
  9. 2025EndoBench: A Comprehensive Evaluation of Multi-Modal Large Language Models for Endoscopy Analysiscited by 13
  10. 2024Aligning the Objective of LLM-based Program Repaircited by 12
  11. 2024MME-Finance: A Multimodal Finance Benchmark for Expert-level Understanding and Reasoningcited by 7
  12. 2025MTBBench: A Multimodal Sequential Clinical Decision-Making Benchmark in Oncologycited by 6
4 more
  1. 2025CBVLM: Training-free Explainable Concept-based Large Vision Language Models for Medical Image Classificationcited by 4
  2. 2025VCRBench: Exploring Long-form Causal Reasoning Capabilities of Large Video Language Modelscited by 4
  3. 2026EHRBench: An Automated and Reliable EHR-based Benchmark for Clinical Decision Making with LLMscited by 2
  4. 2025MedBLINK: Probing Basic Perception in Multimodal Language Models for Medicinecited by 1

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  2. 2025MedHELM: Holistic Evaluation of Large Language Models for Medical Tasks
  3. 2025Beyond the Leaderboard: Rethinking Medical Benchmarks for Large Language Models
  4. 2024A Comprehensive Survey of Large Language Models and Multimodal Large Language Models in Medicine
  5. 2026MEDSYN: Benchmarking Multi-EviDence SYNthesis in Complex Clinical Cases for Multimodal Large Language Models
  6. 2025Med-RewardBench: Benchmarking Reward Models and Judges for Medical Multimodal Large Language Models
  7. 2025BRIDGE: Benchmarking Large Language Models for Understanding Real-world Clinical Practice Text
  8. 2024From Text to Multimodality: Exploring the Evolution and Impact of Large Language Models in Medical Practice