Zero-shot Imputation with Foundation Inference Models for Dynamical Systems
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Abstract (arXiv)
Dynamical systems governed by ordinary differential equations (ODEs) serve as models for a vast number of natural and social phenomena. In this work, we offer a fresh perspective on the classical problem of imputing missing time series data, whose underlying dynamics are assumed to be determined by ODEs. Specifically, we revisit ideas from amortized inference and neural operators, and propose a novel supervised learning framework for zero-shot time series imputation, through parametric functions satisfying some (hidden) ODEs. Our proposal consists of two components. First, a broad probability distribution over the space of ODE solutions, observation times and noise mechanisms, with which we generate a large, synthetic dataset of (hidden) ODE solutions, along with their noisy and sparse observations. Second, a neural recognition model that is trained offline, to map the generated time series onto the spaces of initial conditions and time derivatives of the (hidden) ODE solutions, which we then integrate to impute the missing data. We empirically demonstrate that one and the same (pretrained) recognition model can perform zero-shot imputation across 63 distinct time series with missing values, each sampled from widely different dynamical systems. Likewise, we demonstrate that it can perform zero-shot imputation of missing high-dimensional data in 10 vastly different settings, spanning human motion, air quality, traffic and electricity studies, as well as Navier-Stokes simulations -- without requiring any fine-tuning. What is more, our proposal often outperforms state-of-the-art methods, which are trained on the target datasets. Our pretrained model, repository and tutorials are available online.
Key facts. Cited by 13 papers in the map (data through 7 Oct 2026). Builds on 33 of its 67 references that are in the map. First posted on arXiv 12 Feb 2024.
Builds on
33 of 67 references.
References · 33
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21 more
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Citing papers per year: 2024: 3; 2025: 6; 2026: 4.
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- 2024SSD-TS: Exploring the Potential of Linear State Space Models for Diffusion Models in Time Series Imputationcited by 18
- 2025Panda: A pretrained forecast model for chaotic dynamicscited by 12
- 2025In-Context Learning of Temporal Point Processes with Foundation Inference Modelscited by 7
- 2025Amortized In-Context Mixed Effect Transformer Models: A Zero-Shot Approach for Pharmacokineticscited by 4
- 2025Position: Biology is the Challenge Physics-Informed ML Needs to Evolvecited by 4
- 2024On Foundation Models for Dynamical Systems from Purely Synthetic Datacited by 3
- 2026Foundation Inference Models for Ordinary Differential Equationscited by 3
- 2024Learning System Dynamics without Forgettingcited by 1
- 2025On Foundation Models for Temporal Point Processes to Accelerate Scientific Discoverycited by 0
- 2025Towards Foundation Inference Models that Learn ODEs In-Contextcited by 0
- 2026CINDI: Conditional Imputation and Noisy Data Integrity with Flows in Power Grid Datacited by 0
- 2026EVIL: Evolving Interpretable Algorithms for Zero-Shot Inference on Event Sequences and Time Series with LLMscited by 0
1 more
- 2026Prior-Fitted Functional Flow: In-Context Generative Models for Pharmacokinetics19 Apr 2026
- 2026EVIL: Evolving Interpretable Algorithms for Zero-Shot Inference on Event Sequences and Time Series with LLMs17 Apr 2026
- 2026CINDI: Conditional Imputation and Noisy Data Integrity with Flows in Power Grid Data12 Mar 2026
- 2026Foundation Inference Models for Ordinary Differential Equations9 Feb 2026
- 2025Position: Biology is the Challenge Physics-Informed ML Needs to Evolve29 Oct 2025
- 2025Towards Foundation Inference Models that Learn ODEs In-Context14 Oct 2025
- 2025On Foundation Models for Temporal Point Processes to Accelerate Scientific Discovery14 Oct 2025
- 2025In-Context Learning of Temporal Point Processes with Foundation Inference Models29 Sep 2025
- 2025Amortized In-Context Mixed Effect Transformer Models: A Zero-Shot Approach for Pharmacokinetics21 Aug 2025
- 2025Panda: A pretrained forecast model for chaotic dynamics19 May 2025
- 2024On Foundation Models for Dynamical Systems from Purely Synthetic Data30 Nov 2024
- 2024SSD-TS: Exploring the Potential of Linear State Space Models for Diffusion Models in Time Series Imputation17 Oct 2024
1 more
- 2024Learning System Dynamics without Forgetting30 Jun 2024
- 2025Panda: A pretrained forecast model for chaotic dynamicscited by 12
- 2025In-Context Learning of Temporal Point Processes with Foundation Inference Modelscited by 7
- 2025Amortized In-Context Mixed Effect Transformer Models: A Zero-Shot Approach for Pharmacokineticscited by 4
- 2025Position: Biology is the Challenge Physics-Informed ML Needs to Evolvecited by 4
- 2026Foundation Inference Models for Ordinary Differential Equationscited by 3
- 2024Learning System Dynamics without Forgettingcited by 1
- 2025On Foundation Models for Temporal Point Processes to Accelerate Scientific Discoverycited by 0
- 2025Towards Foundation Inference Models that Learn ODEs In-Contextcited by 0
- 2026CINDI: Conditional Imputation and Noisy Data Integrity with Flows in Power Grid Datacited by 0
- 2026EVIL: Evolving Interpretable Algorithms for Zero-Shot Inference on Event Sequences and Time Series with LLMscited by 0
- 2026Prior-Fitted Functional Flow: In-Context Generative Models for Pharmacokineticscited by 0
- 2026Prior-Fitted Functional Flow: In-Context Generative Models for Pharmacokinetics19 Apr 2026
- 2026EVIL: Evolving Interpretable Algorithms for Zero-Shot Inference on Event Sequences and Time Series with LLMs17 Apr 2026
- 2026CINDI: Conditional Imputation and Noisy Data Integrity with Flows in Power Grid Data12 Mar 2026
- 2026Foundation Inference Models for Ordinary Differential Equations9 Feb 2026
- 2025Position: Biology is the Challenge Physics-Informed ML Needs to Evolve29 Oct 2025
- 2025Towards Foundation Inference Models that Learn ODEs In-Context14 Oct 2025
- 2025On Foundation Models for Temporal Point Processes to Accelerate Scientific Discovery14 Oct 2025
- 2025In-Context Learning of Temporal Point Processes with Foundation Inference Models29 Sep 2025
- 2025Amortized In-Context Mixed Effect Transformer Models: A Zero-Shot Approach for Pharmacokinetics21 Aug 2025
- 2025Panda: A pretrained forecast model for chaotic dynamics19 May 2025
- 2024Learning System Dynamics without Forgetting30 Jun 2024