Towards Concept-based Interpretability of Skin Lesion Diagnosis using Vision-Language Models
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
Concept-based models naturally lend themselves to the development of inherently interpretable skin lesion diagnosis, as medical experts make decisions based on a set of visual patterns of the lesion. Nevertheless, the development of these models depends on the existence of concept-annotated datasets, whose availability is scarce due to the specialized knowledge and expertise required in the annotation process. In this work, we show that vision-language models can be used to alleviate the dependence on a large number of concept-annotated samples. In particular, we propose an embedding learning strategy to adapt CLIP to the downstream task of skin lesion classification using concept-based descriptions as textual embeddings. Our experiments reveal that vision-language models not only attain better accuracy when using concepts as textual embeddings, but also require a smaller number of concept-annotated samples to attain comparable performance to approaches specifically devised for automatic concept generation.
Key facts. Cited by 9 papers in the map (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 11 of its 19 references that are in the map. First posted on arXiv 24 Nov 2023.
Builds on
11 of 19 references.
References · 11
- 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,456
- 2020Concept Bottleneck Modelscited by 1,022
- 2019Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)cited by 657
- 2022Visual Classification via Description from Large Language Modelscited by 331
- 2022Language in a Bottle: Language Model Guided Concept Bottlenecks for Interpretable Image Classificationcited by 310
- 2023Label-Free Concept Bottleneck Modelscited by 282
- 2022Overlooked factors in concept-based explanations: Dataset choice, concept learnability, and human capabilitycited by 46
- 2023Robust and Interpretable Medical Image Classifiers via Concept Bottleneck Modelscited by 40
- 2020On Interpretability of Deep Learning based Skin Lesion Classifiers using Concept Activation Vectorscited by 39
- 2016Deep Learning Ensembles for Melanoma Recognition in Dermoscopy Imagescited by 26
- 2023Coherent Concept-based Explanations in Medical Image and Its Application to Skin Lesion Diagnosiscited by 26
Built on by
Citing papers per year: 2024: 3; 2025: 6.
9 papers.
- 2024Self-eXplainable AI for Medical Image Analysis: A Survey and New Outlookscited by 18
- 2025Enhancing Concept Localization in CLIP-based Concept Bottleneck Modelscited by 6
- 2025CBVLM: Training-free Explainable Concept-based Large Vision Language Models for Medical Image Classificationcited by 4
- 2024Incorporating Expert Rules into Neural Networks in the Framework of Concept-Based Learningcited by 3
- 2024Concept Complement Bottleneck Model for Interpretable Medical Image Diagnosiscited by 3
- 2025Skin Lesion Phenotyping via Nested Multi-modal Contrastive Learningcited by 2
- 2025Towards Interpretable PolSAR Image Classification: Polarimetric Scattering Mechanism Informed Concept Bottleneck and Kolmogorov-Arnold Networkcited by 0
- 2025ViConEx-Med: Visual Concept Explainability via Multi-Concept Token Transformer for Medical Image Analysiscited by 0
- 2025Towards Explainable Skin Cancer Classification: A Dual-Network Attention Model with Lesion Segmentation and Clinical Metadata Fusioncited by 0
- 2025Towards Explainable Skin Cancer Classification: A Dual-Network Attention Model with Lesion Segmentation and Clinical Metadata Fusion20 Oct 2025
- 2025ViConEx-Med: Visual Concept Explainability via Multi-Concept Token Transformer for Medical Image Analysis11 Oct 2025
- 2025Enhancing Concept Localization in CLIP-based Concept Bottleneck Models8 Oct 2025
- 2025Towards Interpretable PolSAR Image Classification: Polarimetric Scattering Mechanism Informed Concept Bottleneck and Kolmogorov-Arnold Network4 Jul 2025
- 2025Skin Lesion Phenotyping via Nested Multi-modal Contrastive Learning29 May 2025
- 2025CBVLM: Training-free Explainable Concept-based Large Vision Language Models for Medical Image Classification21 Jan 2025
- 2024Concept Complement Bottleneck Model for Interpretable Medical Image Diagnosis20 Oct 2024
- 2024Self-eXplainable AI for Medical Image Analysis: A Survey and New Outlooks3 Oct 2024
- 2024Incorporating Expert Rules into Neural Networks in the Framework of Concept-Based Learning22 Feb 2024
Similar, not cited
Close in wording, no citation either way
- 2024A Two-Step Concept-Based Approach for Enhanced Interpretability and Trust in Skin Lesion Diagnosis
- 2026Bridging Research and Practice: A Systematic Evaluation of Generalist and Dermatology-Specific Models in Clinical Skin Lesion Classification
- 2026Open-Linguistic Concept Unified Learning for Cross-Site Interpretable Dermatology Image Diagnosis
- 2025Grounding Multimodal Large Language Models with Quantitative Skin Attributes: A Retrieval Study
- 2025MedGrad E-CLIP: Enhancing Trust and Transparency in AI-Driven Skin Lesion Diagnosis
- 2024Evidential Concept Embedding Models: Towards Reliable Concept Explanations for Skin Disease Diagnosis
- 2025LesionGen: A Concept-Guided Diffusion Model for Dermatology Image Synthesis
- 2026A Vision-Language Foundation Model for Zero-shot Clinical Collaboration and Automated Concept Discovery in Dermatology