Dimensionality Reduction for Improving Out-of-Distribution Detection in Medical Image Segmentation
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Abstract (arXiv)
Clinically deployed segmentation models are known to fail on data outside of their training distribution. As these models perform well on most cases, it is imperative to detect out-of-distribution (OOD) images at inference to protect against automation bias. This work applies the Mahalanobis distance post hoc to the bottleneck features of a Swin UNETR model that segments the liver on T1-weighted magnetic resonance imaging. By reducing the dimensions of the bottleneck features with principal component analysis, OOD images were detected with high performance and minimal computational load.
Key facts. Cited by 6 papers in the map (data through 14 Oct 2026). Builds on 19 of its 29 references that are in the map. First posted on arXiv 7 Aug 2023.
Builds on
19 of 29 references.
References · 19
- 2017On Calibration of Modern Neural Networkscited by 4,960
- 2015Dropout as a Bayesian Approximation: Representing Model Uncertainty in Deep Learningcited by 4,448
- 2016Simple and Scalable Predictive Uncertainty Estimation using Deep Ensemblescited by 3,926
- 2018UMAP: Uniform Manifold Approximation and Projection for Dimension Reductioncited by 2,898
- 2016A Baseline for Detecting Misclassified and Out-of-Distribution Examples in Neural Networkscited by 2,385
- 2018A Simple Unified Framework for Detecting Out-of-Distribution Samples and Adversarial Attackscited by 1,485
- 2017Enhancing The Reliability of Out-of-distribution Image Detection in Neural Networkscited by 1,328
- 2020Energy-based Out-of-distribution Detectioncited by 1,299
- 2022Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Imagescited by 830
- 2021ReAct: Out-of-distribution Detection With Rectified Activationscited by 486
- 2021Self-Supervised Pre-Training of Swin Transformers for 3D Medical Image Analysiscited by 422
- 2018Confounding variables can degrade generalization performance of radiological deep learning modelscited by 379
7 more
- 2022AMOS: A Large-Scale Abdominal Multi-Organ Benchmark for Versatile Medical Image Segmentationcited by 351
- 2020CHAOS Challenge -- Combined (CT-MR) Healthy Abdominal Organ Segmentationcited by 309
- 2021Exploring the Limits of Out-of-Distribution Detectioncited by 283
- 2020A Benchmark of Medical Out of Distribution Detectioncited by 40
- 2022Self-supervised 3D anatomy segmentation using self-distilled masked image transformer (SMIT)cited by 35
- 2021Confidence-based Out-of-Distribution Detection: A Comparative Study and Analysiscited by 34
- 2021Detecting when pre-trained nnU-Net models fail silently for Covid-19 lung lesion segmentationcited by 19
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Citing papers per year: 2024: 3; 2025: 2; 2026: 1.
6 papers.
- 2024Out-of-distribution Detection in Medical Image Analysis: A surveycited by 22
- 2024Robust Conformal Volume Estimation in 3D Medical Imagescited by 4
- 2025COMPASS: Robust Feature Conformal Prediction for Medical Segmentation Metricscited by 4
- 2024Dimensionality Reduction and Nearest Neighbors for Improving Out-of-Distribution Detection in Medical Image Segmentationcited by 1
- 2025Modality-Independent Explainable Detection of Inaccurate Organ Segmentations Using Denoising Autoencoderscited by 0
- 2026Domain Shift in Echocardiography: Interpretable Quantification and Prediction of Cross-Dataset Left Ventricular Segmentationcited by 0
- 2026Domain Shift in Echocardiography: Interpretable Quantification and Prediction of Cross-Dataset Left Ventricular Segmentation22 Jul 2026
- 2025COMPASS: Robust Feature Conformal Prediction for Medical Segmentation Metrics26 Sep 2025
- 2025Modality-Independent Explainable Detection of Inaccurate Organ Segmentations Using Denoising Autoencoders16 Apr 2025
- 2024Dimensionality Reduction and Nearest Neighbors for Improving Out-of-Distribution Detection in Medical Image Segmentation5 Aug 2024
- 2024Robust Conformal Volume Estimation in 3D Medical Images29 Jul 2024
- 2024Out-of-distribution Detection in Medical Image Analysis: A survey28 Apr 2024