Laplacian Segmentation Networks Improve Epistemic Uncertainty Quantification
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Abstract (arXiv)
Image segmentation relies heavily on neural networks which are known to be overconfident, especially when making predictions on out-of-distribution (OOD) images. This is a common scenario in the medical domain due to variations in equipment, acquisition sites, or image corruptions. This work addresses the challenge of OOD detection by proposing Laplacian Segmentation Networks (LSN): methods which jointly model epistemic (model) and aleatoric (data) uncertainty for OOD detection. In doing so, we propose the first Laplace approximation of the weight posterior that scales to large neural networks with skip connections that have high-dimensional outputs. We demonstrate on three datasets that the LSN-modeled parameter distributions, in combination with suitable uncertainty measures, gives superior OOD detection.
Key facts. Cited by 9 papers in the map (data through 7 Oct 2026). Builds on 20 of its 37 references that are in the map. First posted on arXiv 23 Mar 2023.
Builds on
20 of 37 references.
References · 20
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8 more
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Built on by
Citing papers per year: 2023: 1; 2024: 2; 2025: 3; 2026: 3.
9 papers.
- 2024Out-of-distribution Detection in Medical Image Analysis: A surveycited by 22
- 2025Uncertainty Quantification for Machine Learning in Healthcare: A Surveycited by 11
- 2023Uncertainty Estimation for Safety-critical Scene Segmentation via Fine-grained Reward Maximizationcited by 7
- 2024A Review of Bayesian Uncertainty Quantification in Deep Probabilistic Image Segmentationcited by 6
- 2025Aleatoric Uncertainty Medical Image Segmentation Estimation via Flow Matchingcited by 5
- 2026Rethinking Uncertainty Quantification and Entanglement in Image Segmentationcited by 1
- 2025L-FUSION: Laplacian Fetal Ultrasound Segmentation & Uncertainty Estimationcited by 0
- 2026Towards Agnostic and Holistic Universal Image Segmentation with Bit Diffusioncited by 0
- 2026It depends: Incorporating correlations for joint aleatoric and epistemic uncertainties of high-dimensional output spacescited by 0
- 2026It depends: Incorporating correlations for joint aleatoric and epistemic uncertainties of high-dimensional output spaces25 Aug 2026
- 2026Rethinking Uncertainty Quantification and Entanglement in Image Segmentation19 Mar 2026
- 2026Towards Agnostic and Holistic Universal Image Segmentation with Bit Diffusion6 Jan 2026
- 2025Aleatoric Uncertainty Medical Image Segmentation Estimation via Flow Matching30 Jul 2025
- 2025Uncertainty Quantification for Machine Learning in Healthcare: A Survey4 May 2025
- 2025L-FUSION: Laplacian Fetal Ultrasound Segmentation & Uncertainty Estimation7 Mar 2025
- 2024A Review of Bayesian Uncertainty Quantification in Deep Probabilistic Image Segmentation25 Nov 2024
- 2024Out-of-distribution Detection in Medical Image Analysis: A survey28 Apr 2024
- 2023Uncertainty Estimation for Safety-critical Scene Segmentation via Fine-grained Reward Maximization5 Nov 2023