mlsanityData to 14 Oct 2026

On the Effectiveness of Compact Biomedical Transformers

arXiv 2209.03182 ↗First posted 7 Sep 2022cs.CL cs.LGcited by 11

On the map: Knowledge distillation → Knowledge distillation for LLMs

Abstract (arXiv)

Language models pre-trained on biomedical corpora, such as BioBERT, have recently shown promising results on downstream biomedical tasks. Many existing pre-trained models, on the other hand, are resource-intensive and computationally heavy owing to factors such as embedding size, hidden dimension, and number of layers. The natural language processing (NLP) community has developed numerous strategies to compress these models utilising techniques such as pruning, quantisation, and knowledge distillation, resulting in models that are considerably faster, smaller, and subsequently easier to use in practice. By the same token, in this paper we introduce six lightweight models, namely, BioDistilBERT, BioTinyBERT, BioMobileBERT, DistilBioBERT, TinyBioBERT, and CompactBioBERT which are obtained either by knowledge distillation from a biomedical teacher or continual learning on the Pubmed dataset via the Masked Language Modelling (MLM) objective. We evaluate all of our models on three biomedical tasks and compare them with BioBERT-v1.1 to create efficient lightweight models that perform on par with their larger counterparts. All the models will be publicly available on our Huggingface profile at https://huggingface.co/nlpie and the codes used to run the experiments will be available at https://github.com/nlpie-research/Compact-Biomedical-Transformers.

Key facts. Cited by 11 papers in the map (data through 14 Oct 2026). Placed in Knowledge distillation for LLMs, one of 12 directions in Knowledge distillation. Builds on 31 of its 50 references that are in the map. First posted on arXiv 7 Sep 2022.

Builds on

31 of 50 references.

References · 31

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19 more
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Citing papers per year: 2022: 1; 2023: 4; 2024: 4; 2025: 2.

11 papers.

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  1. 2023Benchmarking large language models for biomedical natural language processing applications and recommendations
  2. 2024A Survey for Large Language Models in Biomedicine
  3. 2024Biomedical Large Languages Models Seem not to be Superior to Generalist Models on Unseen Medical Data
  4. 2023BioLORD-2023: Semantic Textual Representations Fusing LLM and Clinical Knowledge Graph Insights
  5. 2025Quantized Large Language Models in Biomedical Natural Language Processing: Evaluation and Recommendation
  6. 2024BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains
  7. 2024BioMamba: Domain-Adaptive Biomedical Language Models
  8. 2026Investigating Model Compression for Neural Machine Translation in the Biomedical Domain