A novel approach for glaucoma classification by wavelet neural networks using graph-based, statisitcal features of qualitatively improved images

In this paper, we have proposed a new glaucoma classification approach that employs a wavelet neural network (WNN) on optimally enhanced retinal images features. To avoid tedious and error prone manual analysis of retinal images by ophthalmologists, computer aided diagnosis (CAD) substantially aids in robust diagnosis. Our objective is to introduce a CAD system with a fresh approach. Retinal image quality improvement is attempted in two phases. The retinal image preprocessing phase improves the brightness and contrast of the image through quantile based histogram modification. It is followed by the image enhancement phase, which involves multi scale morphological operations using image specific dynamic structuring elements for the retinal structure enrichment. Graph based retinal image features in terms of Local Graph Structures (LGS) and Graph Shortest Path (GSP) statistics are extracted from various directions along with the statistical features from the enhanced retinal dataset. WNN is employed to classify glaucoma retinal images with a suitable wavelet activation function. The performance of the WNN classifier is compared with multilayer perceptron neural networks with various datasets. The results show our approach is superior to the existing approaches.