BolT: Fused Window Transformers for fMRI Time Series Analysis
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Abstract (arXiv)
Deep-learning models have enabled performance leaps in analysis of high-dimensional functional MRI (fMRI) data. Yet, many previous methods are suboptimally sensitive for contextual representations across diverse time scales. Here, we present BolT, a blood-oxygen-level-dependent transformer model, for analyzing multi-variate fMRI time series. BolT leverages a cascade of transformer encoders equipped with a novel fused window attention mechanism. Encoding is performed on temporally-overlapped windows within the time series to capture local representations. To integrate information temporally, cross-window attention is computed between base tokens in each window and fringe tokens from neighboring windows. To gradually transition from local to global representations, the extent of window overlap and thereby number of fringe tokens are progressively increased across the cascade. Finally, a novel cross-window regularization is employed to align high-level classification features across the time series. Comprehensive experiments on large-scale public datasets demonstrate the superior performance of BolT against state-of-the-art methods. Furthermore, explanatory analyses to identify landmark time points and regions that contribute most significantly to model decisions corroborate prominent neuroscientific findings in the literature.
Key facts. Cited by 23 papers in the map (data through 14 Oct 2026). Builds on 33 of its 152 references that are in the map. First posted on arXiv 23 May 2022.
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33 of 152 references.
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Citing papers per year: 2022: 1; 2023: 6; 2024: 6; 2025: 6; 2026: 4.
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12 most cited of 19 All 19 (JSON)
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- 2025Brain-Semantoks: Learning Semantic Tokens of Brain Dynamics with a Self-Distilled Foundation Model12 Dec 2025
- 2025VarCoNet: A variability-aware self-supervised framework for functional connectome extraction from resting-state fMRI2 Oct 2025
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- 2025Resting-state fMRI Analysis using Quantum Time-series Transformer31 Aug 2025
- 2025Hierarchical Characterization of Brain Dynamics via State Space-based Vector Quantization28 Jun 2025
- 2024STARFormer: A Novel Spatio-Temporal Aggregation Reorganization Transformer of FMRI for Brain Disorder Diagnosis31 Dec 2024
- 2024Multi-Task Adversarial Variational Autoencoder for Estimating Biological Brain Age with Multimodal Neuroimaging15 Nov 2024
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- 2024Reconstructing physiological signals from fMRI across the adult lifespan26 Aug 2024
12 newest of 19 All 19 (JSON)