Automatic Biomedical Term Clustering by Learning Fine-grained Term Representations
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Abstract (arXiv)
Term clustering is important in biomedical knowledge graph construction. Using similarities between terms embedding is helpful for term clustering. State-of-the-art term embeddings leverage pretrained language models to encode terms, and use synonyms and relation knowledge from knowledge graphs to guide contrastive learning. These embeddings provide close embeddings for terms belonging to the same concept. However, from our probing experiments, these embeddings are not sensitive to minor textual differences which leads to failure for biomedical term clustering. To alleviate this problem, we adjust the sampling strategy in pretraining term embeddings by providing dynamic hard positive and negative samples during contrastive learning to learn fine-grained representations which result in better biomedical term clustering. We name our proposed method as CODER++, and it has been applied in clustering biomedical concepts in the newly released Biomedical Knowledge Graph named BIOS.
Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Builds on 6 of its 15 references that are in the map. First posted on arXiv 1 Apr 2022.
Builds on
6 of 15 references.
References · 6
- 2017Billion-scale similarity search with GPUscited by 2,477
- 2017Decoupled Weight Decay Regularizationcited by 1,722
- 2019Multi-Similarity Loss with General Pair Weighting for Deep Metric Learningcited by 368
- 2020Self-Alignment Pretraining for Biomedical Entity Representationscited by 233
- 2020CODER: Knowledge infused cross-lingual medical term embedding for term normalizationcited by 53
- 2022BIOS: An Algorithmically Generated Biomedical Knowledge Graphcited by 9
Built on by
Citing papers per year: 2022: 1; 2023: 2; 2024: 0; 2025: 2.
5 papers.
- 2023CoRTEx: Contrastive Learning for Representing Terms via Explanations with Applications on Constructing Biomedical Knowledge Graphscited by 5
- 2022Combining Contrastive Learning and Knowledge Graph Embeddings to develop medical word embeddings for the Italian languagecited by 0
- 2023Hierarchical Pretraining for Biomedical Term Embeddingscited by 0
- 2025DR.EHR: Dense Retrieval for Electronic Health Record with Knowledge Injection and Synthetic Datacited by 0
- 2025Automated Hierarchical Graph Construction for Multi-source Electronic Health Recordscited by 0
- 2025Automated Hierarchical Graph Construction for Multi-source Electronic Health Records8 Sep 2025
- 2025DR.EHR: Dense Retrieval for Electronic Health Record with Knowledge Injection and Synthetic Data24 Jul 2025
- 2023CoRTEx: Contrastive Learning for Representing Terms via Explanations with Applications on Constructing Biomedical Knowledge Graphs13 Dec 2023
- 2023Hierarchical Pretraining for Biomedical Term Embeddings1 Jul 2023
- 2022Combining Contrastive Learning and Knowledge Graph Embeddings to develop medical word embeddings for the Italian language9 Nov 2022