mlsanityData to 14 Oct 2026

Learning of Inter-Label Geometric Relationships Using Self-Supervised Learning: Application To Gleason Grade Segmentation

arXiv 2110.00404 ↗First posted 1 Oct 2021eess.IV cs.CVcited by 5

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Abstract (arXiv)

Segmentation of Prostate Cancer (PCa) tissues from Gleason graded histopathology images is vital for accurate diagnosis. Although deep learning (DL) based segmentation methods achieve state-of-the-art accuracy, they rely on large datasets with manual annotations. We propose a method to synthesize for PCa histopathology images by learning the geometrical relationship between different disease labels using self-supervised learning. We use a weakly supervised segmentation approach that uses Gleason score to segment the diseased regions and the resulting segmentation map is used to train a Shape Restoration Network (ShaRe-Net) to predict missing mask segments in a self-supervised manner. Using DenseUNet as the backbone generator architecture we incorporate latent variable sampling to inject diversity in the image generation process and thus improve robustness. Experiments on multiple histopathology datasets demonstrate the superiority of our method over competing image synthesis methods for segmentation tasks. Ablation studies show the benefits of integrating geometry and diversity in generating high-quality images, and our self-supervised approach with limited class-labeled data achieves similar performance as fully supervised learning.

Key facts. Cited by 5 papers in the map (data through 14 Oct 2026). Builds on 56 of its 176 references that are in the map. First posted on arXiv 1 Oct 2021.

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56 of 176 references.

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Cited by year

Citing papers per year: 2021: 1; 2022: 4.

5 papers.

  1. 2022Unsupervised Domain Adaptation Using Feature Disentanglement And GCNs For Medical Image Classificationcited by 5
  2. 2021Multimodal Generalized Zero Shot Learning for Gleason Grading using Self-Supervised Learningcited by 4
  3. 2022Interpretable Saliency Maps And Self-Supervised Learning For Generalized Zero Shot Medical Image Classificationcited by 2
  4. 2022Improved Super Resolution of MR Images Using CNNs and Vision Transformerscited by 1
  5. 2022Cyclic Generative Adversarial Networks With Congruent Image-Report Generation For Explainable Medical Image Analysiscited by 0