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Multidimensional Scaling for Gene Sequence Data with Autoencoders

arXiv 2104.09014 ↗First posted 19 Apr 2021cs.AI cs.DCcited by 0

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Abstract (arXiv)

Multidimensional scaling of gene sequence data has long played a vital role in analysing gene sequence data to identify clusters and patterns. However the computation complexities and memory requirements of state-of-the-art dimensional scaling algorithms make it infeasible to scale to large datasets. In this paper we present an autoencoder-based dimensional reduction model which can easily scale to datasets containing millions of gene sequences, while attaining results comparable to state-of-the-art MDS algorithms with minimal resource requirements. The model also supports out-of-sample data points with a 99.5%+ accuracy based on our experiments. The proposed model is evaluated against DAMDS with a real world fungi gene sequence dataset. The presented results showcase the effectiveness of the autoencoder-based dimension reduction model and its advantages.

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References · 3

  1. 2019PyTorch: An Imperative Style, High-Performance Deep Learning Librarycited by 20,305
  2. 2018UMAP: Uniform Manifold Approximation and Projection for Dimension Reductioncited by 2,898
  3. 2014A survey of dimensionality reduction techniquescited by 50

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