Adversarial Attacks to Machine Learning-Based Smart Healthcare Systems
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Abstract (arXiv)
The increasing availability of healthcare data requires accurate analysis of disease diagnosis, progression, and realtime monitoring to provide improved treatments to the patients. In this context, Machine Learning (ML) models are used to extract valuable features and insights from high-dimensional and heterogeneous healthcare data to detect different diseases and patient activities in a Smart Healthcare System (SHS). However, recent researches show that ML models used in different application domains are vulnerable to adversarial attacks. In this paper, we introduce a new type of adversarial attacks to exploit the ML classifiers used in a SHS. We consider an adversary who has partial knowledge of data distribution, SHS model, and ML algorithm to perform both targeted and untargeted attacks. Employing these adversarial capabilities, we manipulate medical device readings to alter patient status (disease-affected, normal condition, activities, etc.) in the outcome of the SHS. Our attack utilizes five different adversarial ML algorithms (HopSkipJump, Fast Gradient Method, Crafting Decision Tree, Carlini & Wagner, Zeroth Order Optimization) to perform different malicious activities (e.g., data poisoning, misclassify outputs, etc.) on a SHS. Moreover, based on the training and testing phase capabilities of an adversary, we perform white box and black box attacks on a SHS. We evaluate the performance of our work in different SHS settings and medical devices. Our extensive evaluation shows that our proposed adversarial attack can significantly degrade the performance of a ML-based SHS in detecting diseases and normal activities of the patients correctly, which eventually leads to erroneous treatment.
Key facts. Cited by 12 papers in the map (data through 7 Oct 2026). First posted on arXiv 7 Oct 2020.
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Citing papers per year: 2021: 4; 2022: 2; 2023: 2; 2024: 2; 2025: 1; 2026: 1.
12 papers.
- 2023Continual Learning in Medical Image Analysis: A Comprehensive Review of Recent Advancements and Future Prospectscited by 22
- 2021Explainable Deep Learning in Healthcare: A Methodological Survey from an Attribution Viewcited by 15
- 2024Towards Robust Model-Based Reinforcement Learning Against Adversarial Corruptioncited by 12
- 2021Adversarial Attacks and Defenses in Physiological Computing: A Systematic Reviewcited by 7
- 2022Resisting Deep Learning Models Against Adversarial Attack Transferability via Feature Randomizationcited by 5
- 2022Survey of Machine Learning Based Intrusion Detection Methods for Internet of Medical Thingscited by 2
- 2024SoK: Security and Privacy Risks of Healthcare AIcited by 2
- 2021A Novel Framework for Threat Analysis of Machine Learning-based Smart Healthcare Systemscited by 1
- 2021Chromatic and spatial analysis of one-pixel attacks against an image classifiercited by 1
- 2023Adversarial attacks on hybrid classical-quantum Deep Learning models for Histopathological Cancer Detectioncited by 0
- 2025Defending Against Gradient Inversion Attacks for Biomedical Images via Learnable Data Perturbationcited by 0
- 2026Robust Auto-associative Memory via Convolutional Restricted Hopfield Networkscited by 0
- 2026Robust Auto-associative Memory via Convolutional Restricted Hopfield Networks11 Jun 2026
- 2025Defending Against Gradient Inversion Attacks for Biomedical Images via Learnable Data Perturbation19 Mar 2025
- 2024SoK: Security and Privacy Risks of Healthcare AI11 Sep 2024
- 2024Towards Robust Model-Based Reinforcement Learning Against Adversarial Corruption14 Feb 2024
- 2023Continual Learning in Medical Image Analysis: A Comprehensive Review of Recent Advancements and Future Prospects28 Dec 2023
- 2023Adversarial attacks on hybrid classical-quantum Deep Learning models for Histopathological Cancer Detection8 Sep 2023
- 2022Resisting Deep Learning Models Against Adversarial Attack Transferability via Feature Randomization11 Sep 2022
- 2022Survey of Machine Learning Based Intrusion Detection Methods for Internet of Medical Things19 Feb 2022
- 2021Explainable Deep Learning in Healthcare: A Methodological Survey from an Attribution View5 Dec 2021
- 2021Chromatic and spatial analysis of one-pixel attacks against an image classifier28 May 2021
- 2021A Novel Framework for Threat Analysis of Machine Learning-based Smart Healthcare Systems5 Mar 2021
- 2021Adversarial Attacks and Defenses in Physiological Computing: A Systematic Review4 Feb 2021