To BERT or Not To BERT: Comparing Speech and Language-based Approaches for Alzheimer's Disease Detection
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Abstract (arXiv)
Research related to automatically detecting Alzheimer's disease (AD) is important, given the high prevalence of AD and the high cost of traditional methods. Since AD significantly affects the content and acoustics of spontaneous speech, natural language processing and machine learning provide promising techniques for reliably detecting AD. We compare and contrast the performance of two such approaches for AD detection on the recent ADReSS challenge dataset: 1) using domain knowledge-based hand-crafted features that capture linguistic and acoustic phenomena, and 2) fine-tuning Bidirectional Encoder Representations from Transformer (BERT)-based sequence classification models. We also compare multiple feature-based regression models for a neuropsychological score task in the challenge. We observe that fine-tuned BERT models, given the relative importance of linguistics in cognitive impairment detection, outperform feature-based approaches on the AD detection task.
Key facts. Cited by 49 papers in the map (data through 7 Oct 2026). First posted on arXiv 26 Jul 2020.
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Citing papers per year: 2021: 8; 2022: 7; 2023: 6; 2024: 10; 2025: 10; 2026: 8.
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- 2024DALK: Dynamic Co-Augmentation of LLMs and KG to answer Alzheimer's Disease Questions with Scientific Literaturecited by 50
- 2021Comparing Acoustic-based Approaches for Alzheimer's Disease Detectioncited by 21
- 2021Explainable Identification of Dementia from Transcripts using Transformer Networkscited by 19
- 2021Alzheimer's Disease Detection from Spontaneous Speech through Combining Linguistic Complexity and (Dis)Fluency Features with Pretrained Language Modelscited by 13
- 2021Detecting Dementia from Speech and Transcripts using Transformerscited by 13
- 2023Leveraging Pretrained Representations with Task-related Keywords for Alzheimer's Disease Detectioncited by 11
- 2022Exploring linguistic feature and model combination for speech recognition based automatic AD detectioncited by 9
- 2024Useful Blunders: Can Automated Speech Recognition Errors Improve Downstream Dementia Classification?cited by 9
- 2022GPT-D: Inducing Dementia-related Linguistic Anomalies by Deliberate Degradation of Artificial Neural Language Modelscited by 8
- 2024CogniVoice: Multimodal and Multilingual Fusion Networks for Mild Cognitive Impairment Assessment from Spontaneous Speechcited by 8
- 2024Linguistic Features Extracted by GPT-4 Improve Alzheimer's Disease Detection based on Spontaneous Speechcited by 8
- 2025LLMCARE: early detection of cognitive impairment via transformer models enhanced by LLM-generated synthetic datacited by 8
37 more
- 2022Data Augmentation for Dementia Detection in Spoken Languagecited by 7
- 2022Exploiting prompt learning with pre-trained language models for Alzheimer's Disease detectioncited by 6
- 2021Robustness and Sensitivity of BERT Models Predicting Alzheimer's Disease from Textcited by 5
- 2023Alzheimer Disease Classification through ASR-based Transcriptions: Exploring the Impact of Punctuation and Pausescited by 5
- 2024Infusing Acoustic Pause Context into Text-Based Dementia Assessmentcited by 5
- 2021Uncertainty-Aware Boosted Ensembling in Multi-Modal Settingscited by 4
- 2021Alzheimers Dementia Detection using Acoustic & Linguistic features and Pre-Trained BERTcited by 4
- 2023TRESTLE: Toolkit for Reproducible Execution of Speech, Text and Language Experimentscited by 4
- 2023Evaluating Picture Description Speech for Dementia Detection using Image-text Alignmentcited by 4
- 2023Reformulating NLP tasks to Capture Longitudinal Manifestation of Language Disorders in People with Dementiacited by 4
- 2024Cognitive Insights Across Languages: Enhancing Multimodal Interview Analysiscited by 4
- 2024A Systematic Review of NLP for Dementia -- Tasks, Datasets and Opportunitiescited by 4
- 2021Towards Interpretability of Speech Pause in Dementia Detection using Adversarial Learningcited by 3
- 2022The Far Side of Failure: Investigating the Impact of Speech Recognition Errors on Subsequent Dementia Classificationcited by 2
- 2023Learning Co-Speech Gesture for Multimodal Aphasia Type Detectioncited by 2
- 2024Confidence Estimation for Automatic Detection of Depression and Alzheimer's Disease Based on Clinical Interviewscited by 2
- 2025Zero-Shot Cognitive Impairment Detection from Speech Using AudioLLMcited by 2
- 2022Impact of Environmental Noise on Alzheimer's Disease Detection from Speech: Should You Let a Baby Cry?cited by 1
- 2024On the Within-class Variation Issue in Alzheimer's Disease Detectioncited by 1
- 2024Deep Insights into Cognitive Decline: A Survey of Leveraging Non-Intrusive Modalities with Deep Learning Techniquescited by 1
- 2025Automated Extraction of Spatio-Semantic Graphs for Identifying Cognitive Impairmentcited by 1
- 2025Alzheimer's Dementia Detection Using Perplexity from Paired Large Language Modelscited by 1
- 2025Advancing Automated Spatio-Semantic Analysis in Picture Description Using Language Modelscited by 1
- 2022Acoustic-Linguistic Features for Modeling Neurological Task Score in Alzheimer'scited by 0
- 2025Enhancing and Exploring Mild Cognitive Impairment Detection with W2V-BERT-2.0cited by 0
- 2025Dementia Insights: A Context-Based MultiModal Approachcited by 0
- 2025Reverse-Speech-Finder: A Neural Network Backtracking Architecture for Generating Alzheimer's Disease Speech Samples and Improving Diagnosis Performancecited by 0
- 2025Understanding Dementia Speech Alignment with Diffusion-Based Image Generationcited by 0
- 2025Beyond surface form: A pipeline for semantic analysis in Alzheimer's Disease detection from spontaneous speechcited by 0
- 2026What Do LLMs Know About Alzheimer's Disease? Multi-loss Fine-Tuning and Probing for AD Detectioncited by 0
- 2026Agentic Cognitive Profiling: Realigning Automated Alzheimer's Disease Detection with Clinical Construct Validitycited by 0
- 2026Can Large Language Models Imitate Human Speech for Clinical Assessment? LLM-Driven Data Augmentation for Cognitive Score Predictioncited by 0
- 2026A Multimodal Framework for Dementia Detection via Linguistic and Acoustic Representation Learningcited by 0
- 2026Listening Between the Lines: Joint Learning of ASR Embeddings and LLM-Augmented Linguistics for Dementia Detectioncited by 0
- 2026Gated Multi-Graph Fusion via Graph Attention Networks for Alzheimer's Disease Detectioncited by 0
- 2026Activation-Guided Neuron Intervention to Induce Alzheimer's-Related Computational Language Phenotypes in a Large Language Modelcited by 0
- 2026Why Alzheimer's Speech Screening Fails to Generalize: Bridging the Deployment Gap via Cross-Corpus Evidence Anchoringcited by 0
- 2026Why Alzheimer's Speech Screening Fails to Generalize: Bridging the Deployment Gap via Cross-Corpus Evidence Anchoring25 Sep 2026
- 2026Activation-Guided Neuron Intervention to Induce Alzheimer's-Related Computational Language Phenotypes in a Large Language Model4 Aug 2026
- 2026Gated Multi-Graph Fusion via Graph Attention Networks for Alzheimer's Disease Detection30 Jun 2026
- 2026Listening Between the Lines: Joint Learning of ASR Embeddings and LLM-Augmented Linguistics for Dementia Detection26 Jun 2026
- 2026A Multimodal Framework for Dementia Detection via Linguistic and Acoustic Representation Learning25 May 2026
- 2026Can Large Language Models Imitate Human Speech for Clinical Assessment? LLM-Driven Data Augmentation for Cognitive Score Prediction15 May 2026
- 2026Agentic Cognitive Profiling: Realigning Automated Alzheimer's Disease Detection with Clinical Construct Validity18 Mar 2026
- 2026What Do LLMs Know About Alzheimer's Disease? Multi-loss Fine-Tuning and Probing for AD Detection20 Jan 2026
- 2025Beyond surface form: A pipeline for semantic analysis in Alzheimer's Disease detection from spontaneous speech15 Dec 2025
- 2025Advancing Automated Spatio-Semantic Analysis in Picture Description Using Language Models30 Sep 2025
- 2025Understanding Dementia Speech Alignment with Diffusion-Based Image Generation12 Aug 2025
- 2025LLMCARE: early detection of cognitive impairment via transformer models enhanced by LLM-generated synthetic data8 Aug 2025
37 more
- 2025Zero-Shot Cognitive Impairment Detection from Speech Using AudioLLM20 Jun 2025
- 2025Alzheimer's Dementia Detection Using Perplexity from Paired Large Language Models11 Jun 2025
- 2025Reverse-Speech-Finder: A Neural Network Backtracking Architecture for Generating Alzheimer's Disease Speech Samples and Improving Diagnosis Performance23 May 2025
- 2025Dementia Insights: A Context-Based MultiModal Approach3 Mar 2025
- 2025Automated Extraction of Spatio-Semantic Graphs for Identifying Cognitive Impairment2 Feb 2025
- 2025Enhancing and Exploring Mild Cognitive Impairment Detection with W2V-BERT-2.027 Jan 2025
- 2024Linguistic Features Extracted by GPT-4 Improve Alzheimer's Disease Detection based on Spontaneous Speech20 Dec 2024
- 2024Deep Insights into Cognitive Decline: A Survey of Leveraging Non-Intrusive Modalities with Deep Learning Techniques24 Oct 2024
- 2024A Systematic Review of NLP for Dementia -- Tasks, Datasets and Opportunities29 Sep 2024
- 2024On the Within-class Variation Issue in Alzheimer's Disease Detection22 Sep 2024
- 2024Infusing Acoustic Pause Context into Text-Based Dementia Assessment27 Aug 2024
- 2024Confidence Estimation for Automatic Detection of Depression and Alzheimer's Disease Based on Clinical Interviews29 Jul 2024
- 2024CogniVoice: Multimodal and Multilingual Fusion Networks for Mild Cognitive Impairment Assessment from Spontaneous Speech18 Jul 2024
- 2024Cognitive Insights Across Languages: Enhancing Multimodal Interview Analysis11 Jun 2024
- 2024DALK: Dynamic Co-Augmentation of LLMs and KG to answer Alzheimer's Disease Questions with Scientific Literature8 May 2024
- 2024Useful Blunders: Can Automated Speech Recognition Errors Improve Downstream Dementia Classification?10 Jan 2024
- 2023Learning Co-Speech Gesture for Multimodal Aphasia Type Detection18 Oct 2023
- 2023Reformulating NLP tasks to Capture Longitudinal Manifestation of Language Disorders in People with Dementia15 Oct 2023
- 2023Evaluating Picture Description Speech for Dementia Detection using Image-text Alignment11 Aug 2023
- 2023Alzheimer Disease Classification through ASR-based Transcriptions: Exploring the Impact of Punctuation and Pauses6 Jun 2023
- 2023Leveraging Pretrained Representations with Task-related Keywords for Alzheimer's Disease Detection14 Mar 2023
- 2023TRESTLE: Toolkit for Reproducible Execution of Speech, Text and Language Experiments14 Feb 2023
- 2022The Far Side of Failure: Investigating the Impact of Speech Recognition Errors on Subsequent Dementia Classification11 Nov 2022
- 2022Exploiting prompt learning with pre-trained language models for Alzheimer's Disease detection29 Oct 2022
- 2022Acoustic-Linguistic Features for Modeling Neurological Task Score in Alzheimer's13 Sep 2022
- 2022Exploring linguistic feature and model combination for speech recognition based automatic AD detection28 Jun 2022
- 2022Data Augmentation for Dementia Detection in Spoken Language26 Jun 2022
- 2022Impact of Environmental Noise on Alzheimer's Disease Detection from Speech: Should You Let a Baby Cry?31 Mar 2022
- 2022GPT-D: Inducing Dementia-related Linguistic Anomalies by Deliberate Degradation of Artificial Neural Language Models25 Mar 2022
- 2021Towards Interpretability of Speech Pause in Dementia Detection using Adversarial Learning14 Nov 2021
- 2021Detecting Dementia from Speech and Transcripts using Transformers27 Oct 2021
- 2021Robustness and Sensitivity of BERT Models Predicting Alzheimer's Disease from Text24 Sep 2021
- 2021Alzheimers Dementia Detection using Acoustic & Linguistic features and Pre-Trained BERT22 Sep 2021
- 2021Explainable Identification of Dementia from Transcripts using Transformer Networks14 Sep 2021
- 2021Alzheimer's Disease Detection from Spontaneous Speech through Combining Linguistic Complexity and (Dis)Fluency Features with Pretrained Language Models16 Jun 2021
- 2021Comparing Acoustic-based Approaches for Alzheimer's Disease Detection3 Jun 2021
- 2021Uncertainty-Aware Boosted Ensembling in Multi-Modal Settings21 Apr 2021
- 2024DALK: Dynamic Co-Augmentation of LLMs and KG to answer Alzheimer's Disease Questions with Scientific Literaturecited by 50
- 2021Comparing Acoustic-based Approaches for Alzheimer's Disease Detectioncited by 21
- 2021Explainable Identification of Dementia from Transcripts using Transformer Networkscited by 19
- 2021Alzheimer's Disease Detection from Spontaneous Speech through Combining Linguistic Complexity and (Dis)Fluency Features with Pretrained Language Modelscited by 13
- 2021Detecting Dementia from Speech and Transcripts using Transformerscited by 13
- 2023Leveraging Pretrained Representations with Task-related Keywords for Alzheimer's Disease Detectioncited by 11
- 2022Exploring linguistic feature and model combination for speech recognition based automatic AD detectioncited by 9
- 2024Useful Blunders: Can Automated Speech Recognition Errors Improve Downstream Dementia Classification?cited by 9
- 2022GPT-D: Inducing Dementia-related Linguistic Anomalies by Deliberate Degradation of Artificial Neural Language Modelscited by 8
- 2024CogniVoice: Multimodal and Multilingual Fusion Networks for Mild Cognitive Impairment Assessment from Spontaneous Speechcited by 8
- 2024Linguistic Features Extracted by GPT-4 Improve Alzheimer's Disease Detection based on Spontaneous Speechcited by 8
- 2022Data Augmentation for Dementia Detection in Spoken Languagecited by 7
12 most cited of 46 All 46 (JSON)
- 2026Why Alzheimer's Speech Screening Fails to Generalize: Bridging the Deployment Gap via Cross-Corpus Evidence Anchoring25 Sep 2026
- 2026Activation-Guided Neuron Intervention to Induce Alzheimer's-Related Computational Language Phenotypes in a Large Language Model4 Aug 2026
- 2026Gated Multi-Graph Fusion via Graph Attention Networks for Alzheimer's Disease Detection30 Jun 2026
- 2026Listening Between the Lines: Joint Learning of ASR Embeddings and LLM-Augmented Linguistics for Dementia Detection26 Jun 2026
- 2026A Multimodal Framework for Dementia Detection via Linguistic and Acoustic Representation Learning25 May 2026
- 2026Can Large Language Models Imitate Human Speech for Clinical Assessment? LLM-Driven Data Augmentation for Cognitive Score Prediction15 May 2026
- 2026What Do LLMs Know About Alzheimer's Disease? Multi-loss Fine-Tuning and Probing for AD Detection20 Jan 2026
- 2025Beyond surface form: A pipeline for semantic analysis in Alzheimer's Disease detection from spontaneous speech15 Dec 2025
- 2025Advancing Automated Spatio-Semantic Analysis in Picture Description Using Language Models30 Sep 2025
- 2025Zero-Shot Cognitive Impairment Detection from Speech Using AudioLLM20 Jun 2025
- 2025Alzheimer's Dementia Detection Using Perplexity from Paired Large Language Models11 Jun 2025
- 2025Reverse-Speech-Finder: A Neural Network Backtracking Architecture for Generating Alzheimer's Disease Speech Samples and Improving Diagnosis Performance23 May 2025
12 newest of 46 All 46 (JSON)