Parkinson's Disease Detection Using Ensemble Architecture from MR Images

Parkinson's Disease(PD) is one of the major nervous system disorders that affect people over 60. PD can cause cognitive impairments. In this work, we explore various approaches to identify Parkinson's using Magnetic Resonance (MR) T1 images of the brain. We experiment with ensemble architectures combining some winning Convolutional Neural Network models of ImageNet Large Scale Visual Recognition Challenge (ILSVRC) and propose two architectures. We find that detection accuracy increases drastically when we focus on the Gray Matter (GM) and White Matter (WM) regions from the MR images instead of using whole MR images. We achieved an average accuracy of 94.7% using smoothed GM and WM extracts and one of our proposed architectures. We also perform occlusion analysis and determine which brain areas are relevant in the architecture decision making process.