Substra: a framework for privacy-preserving, traceable and collaborative Machine Learning
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Abstract (arXiv)
Machine learning is promising, but it often needs to process vast amounts of sensitive data which raises concerns about privacy. In this white-paper, we introduce Substra, a distributed framework for privacy-preserving, traceable and collaborative Machine Learning. Substra gathers data providers and algorithm designers into a network of nodes that can train models on demand but under advanced permission regimes. To guarantee data privacy, Substra implements distributed learning: the data never leave their nodes; only algorithms, predictive models and non-sensitive metadata are exchanged on the network. The computations are orchestrated by a Distributed Ledger Technology which guarantees traceability and authenticity of information without needing to trust a third party. Although originally developed for Healthcare applications, Substra is not data, algorithm or programming language specific. It supports many types of computation plans including parallel computation plan commonly used in Federated Learning. With appropriate guidelines, it can be deployed for numerous Machine Learning use-cases with data or algorithm providers where trust is limited.
Key facts. Cited by 14 papers in the map (data through 14 Oct 2026). First posted on arXiv 25 Oct 2019.
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Citing papers per year: 2022: 3; 2023: 3; 2024: 5; 2025: 1; 2026: 2.
14 papers.
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- 2022FLamby: Datasets and Benchmarks for Cross-Silo Federated Learning in Realistic Healthcare Settingscited by 125
- 2022Federated Learning for Medical Applications: A Taxonomy, Current Trends, Challenges, and Future Research Directionscited by 35
- 2024A Survey on Efficient Federated Learning Methods for Foundation Model Trainingcited by 29
- 2022Federated Multilingual Models for Medical Transcript Analysiscited by 11
- 2023Fed-BioMed: Open, Transparent and Trusted Federated Learning for Real-world Healthcare Applicationscited by 10
- 2024Flight: A FaaS-Based Framework for Complex and Hierarchical Federated Learningcited by 3
- 2025FL-APU: A Software Architecture to Ease Practical Implementation of Cross-Silo Federated Learningcited by 3
- 2023FedECA: Federated External Control Arms for Causal Inference with Time-To-Event Data in Distributed Settingscited by 2
- 2024Flotta: a Secure and Flexible Spark-inspired Federated Learning Frameworkcited by 1
- 2026Scalability and Performance Evaluation of Federated Learning Frameworks: A Comparative Analysiscited by 1
- 2023A Comprehensive Empirical Study of Bugs in Open-Source Federated Learning Frameworkscited by 0
- 2024Federated Computing -- Survey on Building Blocks, Extensions and Systemscited by 0
- 2026Making Cross-Continental Federated Learning Repeatable with FLIP: a Multi-Application Study28 Sep 2026
- 2026Scalability and Performance Evaluation of Federated Learning Frameworks: A Comparative Analysis14 Sep 2026
- 2025FL-APU: A Software Architecture to Ease Practical Implementation of Cross-Silo Federated Learning31 Jan 2025
- 2024Flight: A FaaS-Based Framework for Complex and Hierarchical Federated Learning24 Sep 2024
- 2024Flotta: a Secure and Flexible Spark-inspired Federated Learning Framework20 Sep 2024
- 2024Where is the Testbed for my Federated Learning Research?19 Jul 2024
- 2024Federated Computing -- Survey on Building Blocks, Extensions and Systems3 Apr 2024
- 2024A Survey on Efficient Federated Learning Methods for Foundation Model Training9 Jan 2024
- 2023FedECA: Federated External Control Arms for Causal Inference with Time-To-Event Data in Distributed Settings28 Nov 2023
- 2023A Comprehensive Empirical Study of Bugs in Open-Source Federated Learning Frameworks9 Aug 2023
- 2023Fed-BioMed: Open, Transparent and Trusted Federated Learning for Real-world Healthcare Applications24 Apr 2023
- 2022Federated Multilingual Models for Medical Transcript Analysis4 Nov 2022
- 2022FLamby: Datasets and Benchmarks for Cross-Silo Federated Learning in Realistic Healthcare Settingscited by 125
- 2022Federated Learning for Medical Applications: A Taxonomy, Current Trends, Challenges, and Future Research Directionscited by 35
- 2024A Survey on Efficient Federated Learning Methods for Foundation Model Trainingcited by 29
- 2022Federated Multilingual Models for Medical Transcript Analysiscited by 11
- 2023Fed-BioMed: Open, Transparent and Trusted Federated Learning for Real-world Healthcare Applicationscited by 10
- 2024Flight: A FaaS-Based Framework for Complex and Hierarchical Federated Learningcited by 3
- 2025FL-APU: A Software Architecture to Ease Practical Implementation of Cross-Silo Federated Learningcited by 3
- 2023FedECA: Federated External Control Arms for Causal Inference with Time-To-Event Data in Distributed Settingscited by 2
- 2024Flotta: a Secure and Flexible Spark-inspired Federated Learning Frameworkcited by 1
- 2026Scalability and Performance Evaluation of Federated Learning Frameworks: A Comparative Analysiscited by 1
- 2023A Comprehensive Empirical Study of Bugs in Open-Source Federated Learning Frameworkscited by 0
- 2024Federated Computing -- Survey on Building Blocks, Extensions and Systemscited by 0
12 most cited of 14 All 14 (JSON)
- 2026Making Cross-Continental Federated Learning Repeatable with FLIP: a Multi-Application Study28 Sep 2026
- 2026Scalability and Performance Evaluation of Federated Learning Frameworks: A Comparative Analysis14 Sep 2026
- 2025FL-APU: A Software Architecture to Ease Practical Implementation of Cross-Silo Federated Learning31 Jan 2025
- 2024Flight: A FaaS-Based Framework for Complex and Hierarchical Federated Learning24 Sep 2024
- 2024Flotta: a Secure and Flexible Spark-inspired Federated Learning Framework20 Sep 2024
- 2024Where is the Testbed for my Federated Learning Research?19 Jul 2024
- 2024Federated Computing -- Survey on Building Blocks, Extensions and Systems3 Apr 2024
- 2024A Survey on Efficient Federated Learning Methods for Foundation Model Training9 Jan 2024
- 2023FedECA: Federated External Control Arms for Causal Inference with Time-To-Event Data in Distributed Settings28 Nov 2023
- 2023A Comprehensive Empirical Study of Bugs in Open-Source Federated Learning Frameworks9 Aug 2023
- 2023Fed-BioMed: Open, Transparent and Trusted Federated Learning for Real-world Healthcare Applications24 Apr 2023
- 2022Federated Multilingual Models for Medical Transcript Analysis4 Nov 2022
12 newest of 14 All 14 (JSON)