Clinical Concept Embeddings Learned from Massive Sources of Multimodal Medical Data
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Abstract (arXiv)
Word embeddings are a popular approach to unsupervised learning of word relationships that are widely used in natural language processing. In this article, we present a new set of embeddings for medical concepts learned using an extremely large collection of multimodal medical data. Leaning on recent theoretical insights, we demonstrate how an insurance claims database of 60 million members, a collection of 20 million clinical notes, and 1.7 million full text biomedical journal articles can be combined to embed concepts into a common space, resulting in the largest ever set of embeddings for 108,477 medical concepts. To evaluate our approach, we present a new benchmark methodology based on statistical power specifically designed to test embeddings of medical concepts. Our approach, called cui2vec, attains state-of-the-art performance relative to previous methods in most instances. Finally, we provide a downloadable set of pre-trained embeddings for other researchers to use, as well as an online tool for interactive exploration of the cui2vec embeddings
Key facts. Cited by 35 papers in the map (data through 14 Oct 2026). First posted on arXiv 4 Apr 2018.
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Citing papers per year: 2021: 8; 2022: 4; 2023: 7; 2024: 4; 2025: 7; 2026: 5.
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- 2024Vision-Language Models for Medical Report Generation and Visual Question Answering: A Reviewcited by 125
- 2021CEHR-BERT: Incorporating temporal information from structured EHR data to improve prediction taskscited by 76
- 2022Generating Scientific Claims for Zero-Shot Scientific Fact Checkingcited by 59
- 2021Neural Natural Language Processing for Unstructured Data in Electronic Health Records: a Reviewcited by 35
- 2024EHRMamba: Towards Generalizable and Scalable Foundation Models for Electronic Health Recordscited by 32
- 2022Multimodal Learning on Graphs for Disease Relation Extractioncited by 15
- 2021Natural Language Processing for Smart Healthcarecited by 14
- 2022Multimodal data matters: language model pre-training over structured and unstructured electronic health recordscited by 13
- 2021Multi-source Learning via Completion of Block-wise Overlapping Noisy Matricescited by 10
- 2021Probing Pre-Trained Language Models for Disease Knowledgecited by 10
- 2023Bioformer: an efficient transformer language model for biomedical text miningcited by 9
- 2021A Hybrid Approach to Measure Semantic Relatedness in Biomedical Conceptscited by 5
23 more
- 2023Inference of Dependency Knowledge Graph for Electronic Health Recordscited by 5
- 2025Representation learning to advance multi-institutional studies with electronic health record data from US and Francecited by 5
- 2022Consensus Knowledge Graph Learning via Multi-view Sparse Low Rank Block Modelcited by 3
- 2024Contrastive Learning on Multimodal Analysis of Electronic Health Recordscited by 3
- 2025Integration of Large Language Models and Traditional Deep Learning for Social Determinants of Health Predictioncited by 3
- 2023Multi-modal Graph Learning over UMLS Knowledge Graphscited by 2
- 2021TextEssence: A Tool for Interactive Analysis of Semantic Shifts Between Corporacited by 1
- 2021Transfer Learning in Electronic Health Records through Clinical Concept Embeddingcited by 1
- 2023Knowledge Graph Embeddings for Multi-Lingual Structured Representations of Radiology Reportscited by 1
- 2024Estimating Text Similarity based on Semantic Concept Embeddingscited by 1
- 2025Less Context, Same Performance: A RAG Framework for Resource-Efficient LLM-Based Clinical NLPcited by 1
- 2025KEEP: Integrating Medical Ontologies with Clinical Data for Robust Code Embeddingscited by 1
- 2023Predefined domain specific embeddings of food concepts and recipes: A case study on heterogeneous recipe datasetscited by 0
- 2023LATTE: Label-efficient Incident Phenotyping from Longitudinal Electronic Health Recordscited by 0
- 2023Hierarchical Pretraining for Biomedical Term Embeddingscited by 0
- 2025Latent Factor Point Processes for Patient Representation in Electronic Health Recordscited by 0
- 2025Automated Hierarchical Graph Construction for Multi-source Electronic Health Recordscited by 0
- 2025A Common Pipeline for Harmonizing Electronic Health Record Data for Translational Researchcited by 0
- 2026Automatic Cardiac Risk Management Classification using large-context Electronic Patients Health Recordscited by 0
- 2026LatentVerse: A Framework for Understanding Shared and Modality-Specific Information in Multimodal Latent Representationscited by 0
- 2026HCOE: Hyperbolic Clinical Ontology Embeddings from Biomedical Language Modelscited by 0
- 2026SMI: Ontology-Grounded Semantic IDs for Hierarchy-Aware Medical Concept Representationcited by 0
- 2026A Two-Level Clinical Novelty Prioritization Framework for Disease Trajectories Discovered from Longitudinal Electronic Health Recordscited by 0
- 2026A Two-Level Clinical Novelty Prioritization Framework for Disease Trajectories Discovered from Longitudinal Electronic Health Records14 Oct 2026
- 2026SMI: Ontology-Grounded Semantic IDs for Hierarchy-Aware Medical Concept Representation13 Oct 2026
- 2026HCOE: Hyperbolic Clinical Ontology Embeddings from Biomedical Language Models25 Sep 2026
- 2026LatentVerse: A Framework for Understanding Shared and Modality-Specific Information in Multimodal Latent Representations11 Sep 2026
- 2026Automatic Cardiac Risk Management Classification using large-context Electronic Patients Health Records10 Mar 2026
- 2025KEEP: Integrating Medical Ontologies with Clinical Data for Robust Code Embeddings6 Oct 2025
- 2025A Common Pipeline for Harmonizing Electronic Health Record Data for Translational Research10 Sep 2025
- 2025Automated Hierarchical Graph Construction for Multi-source Electronic Health Records8 Sep 2025
- 2025Latent Factor Point Processes for Patient Representation in Electronic Health Records28 Aug 2025
- 2025Less Context, Same Performance: A RAG Framework for Resource-Efficient LLM-Based Clinical NLP23 May 2025
- 2025Integration of Large Language Models and Traditional Deep Learning for Social Determinants of Health Prediction6 May 2025
- 2025Representation learning to advance multi-institutional studies with electronic health record data from US and France12 Feb 2025
23 more
- 2024EHRMamba: Towards Generalizable and Scalable Foundation Models for Electronic Health Records23 May 2024
- 2024Contrastive Learning on Multimodal Analysis of Electronic Health Records22 Mar 2024
- 2024Vision-Language Models for Medical Report Generation and Visual Question Answering: A Review4 Mar 2024
- 2024Estimating Text Similarity based on Semantic Concept Embeddings9 Jan 2024
- 2023Inference of Dependency Knowledge Graph for Electronic Health Records25 Dec 2023
- 2023Knowledge Graph Embeddings for Multi-Lingual Structured Representations of Radiology Reports2 Sep 2023
- 2023Multi-modal Graph Learning over UMLS Knowledge Graphs10 Jul 2023
- 2023Hierarchical Pretraining for Biomedical Term Embeddings1 Jul 2023
- 2023LATTE: Label-efficient Incident Phenotyping from Longitudinal Electronic Health Records19 May 2023
- 2023Bioformer: an efficient transformer language model for biomedical text mining3 Feb 2023
- 2023Predefined domain specific embeddings of food concepts and recipes: A case study on heterogeneous recipe datasets2 Feb 2023
- 2022Consensus Knowledge Graph Learning via Multi-view Sparse Low Rank Block Model28 Sep 2022
- 2022Generating Scientific Claims for Zero-Shot Scientific Fact Checking24 Mar 2022
- 2022Multimodal Learning on Graphs for Disease Relation Extraction16 Mar 2022
- 2022Multimodal data matters: language model pre-training over structured and unstructured electronic health records25 Jan 2022
- 2021CEHR-BERT: Incorporating temporal information from structured EHR data to improve prediction tasks10 Nov 2021
- 2021Natural Language Processing for Smart Healthcare19 Oct 2021
- 2021Transfer Learning in Electronic Health Records through Clinical Concept Embedding27 Jul 2021
- 2021Neural Natural Language Processing for Unstructured Data in Electronic Health Records: a Review7 Jul 2021
- 2021Probing Pre-Trained Language Models for Disease Knowledge14 Jun 2021
- 2021Multi-source Learning via Completion of Block-wise Overlapping Noisy Matrices21 May 2021
- 2021TextEssence: A Tool for Interactive Analysis of Semantic Shifts Between Corpora19 Mar 2021
- 2021A Hybrid Approach to Measure Semantic Relatedness in Biomedical Concepts25 Jan 2021
- 2021CEHR-BERT: Incorporating temporal information from structured EHR data to improve prediction taskscited by 76
- 2022Generating Scientific Claims for Zero-Shot Scientific Fact Checkingcited by 59
- 2021Neural Natural Language Processing for Unstructured Data in Electronic Health Records: a Reviewcited by 35
- 2024EHRMamba: Towards Generalizable and Scalable Foundation Models for Electronic Health Recordscited by 32
- 2022Multimodal Learning on Graphs for Disease Relation Extractioncited by 15
- 2021Natural Language Processing for Smart Healthcarecited by 14
- 2022Multimodal data matters: language model pre-training over structured and unstructured electronic health recordscited by 13
- 2021Multi-source Learning via Completion of Block-wise Overlapping Noisy Matricescited by 10
- 2021Probing Pre-Trained Language Models for Disease Knowledgecited by 10
- 2023Bioformer: an efficient transformer language model for biomedical text miningcited by 9
- 2021A Hybrid Approach to Measure Semantic Relatedness in Biomedical Conceptscited by 5
- 2023Inference of Dependency Knowledge Graph for Electronic Health Recordscited by 5
12 most cited of 33 All 33 (JSON)
- 2026A Two-Level Clinical Novelty Prioritization Framework for Disease Trajectories Discovered from Longitudinal Electronic Health Records14 Oct 2026
- 2026SMI: Ontology-Grounded Semantic IDs for Hierarchy-Aware Medical Concept Representation13 Oct 2026
- 2026HCOE: Hyperbolic Clinical Ontology Embeddings from Biomedical Language Models25 Sep 2026
- 2026LatentVerse: A Framework for Understanding Shared and Modality-Specific Information in Multimodal Latent Representations11 Sep 2026
- 2026Automatic Cardiac Risk Management Classification using large-context Electronic Patients Health Records10 Mar 2026
- 2025KEEP: Integrating Medical Ontologies with Clinical Data for Robust Code Embeddings6 Oct 2025
- 2025A Common Pipeline for Harmonizing Electronic Health Record Data for Translational Research10 Sep 2025
- 2025Automated Hierarchical Graph Construction for Multi-source Electronic Health Records8 Sep 2025
- 2025Latent Factor Point Processes for Patient Representation in Electronic Health Records28 Aug 2025
- 2025Integration of Large Language Models and Traditional Deep Learning for Social Determinants of Health Prediction6 May 2025
- 2025Representation learning to advance multi-institutional studies with electronic health record data from US and France12 Feb 2025
- 2024EHRMamba: Towards Generalizable and Scalable Foundation Models for Electronic Health Records23 May 2024
12 newest of 33 All 33 (JSON)