Deep Retinal Image Understanding
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Abstract (arXiv)
This paper presents Deep Retinal Image Understanding (DRIU), a unified framework of retinal image analysis that provides both retinal vessel and optic disc segmentation. We make use of deep Convolutional Neural Networks (CNNs), which have proven revolutionary in other fields of computer vision such as object detection and image classification, and we bring their power to the study of eye fundus images. DRIU uses a base network architecture on which two set of specialized layers are trained to solve both the retinal vessel and optic disc segmentation. We present experimental validation, both qualitative and quantitative, in four public datasets for these tasks. In all of them, DRIU presents super-human performance, that is, it shows results more consistent with a gold standard than a second human annotator used as control.
Key facts. Cited by 35 papers in the map (data through 7 Oct 2026). First posted on arXiv 5 Sep 2016.
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Citing papers per year: 2021: 11; 2022: 10; 2023: 5; 2024: 4; 2025: 3; 2026: 2.
35 papers.
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- 2021Applications of Deep Learning in Fundus Images: A Reviewcited by 59
- 2021Uncertainty guided semi-supervised segmentation of retinal layers in OCT imagescited by 29
- 2022AADG: Automatic Augmentation for Domain Generalization on Retinal Image Segmentationcited by 18
- 2021Sequential vessel segmentation via deep channel attention networkcited by 14
- 2022MKIS-Net: A Light-Weight Multi-Kernel Network for Medical Image Segmentationcited by 13
- 2021RC-Net: A Convolutional Neural Network for Retinal Vessel Segmentationcited by 12
- 2022Local Intensity Order Transformation for Robust Curvilinear Object Segmentationcited by 12
- 2023Feature Enhancer Segmentation Network (FES-Net) for Vessel Segmentationcited by 10
- 2023ESDMR-Net: A Lightweight Network With Expand-Squeeze and Dual Multiscale Residual Connections for Medical Image Segmentationcited by 9
- 2024Advancing Medical Image Segmentation with Mini-Net: A Lightweight Solution Tailored for Efficient Segmentation of Medical Imagescited by 9
- 2022Orientation and Context Entangled Network for Retinal Vessel Segmentationcited by 8
- 2021DR-VNet: Retinal Vessel Segmentation via Dense Residual UNetcited by 6
23 more
- 2021An Analysis of the Influence of Transfer Learning When Measuring the Tortuosity of Blood Vesselscited by 4
- 2022Enforcing connectivity of 3D linear structures using their 2D projectionscited by 3
- 2022Affinity Feature Strengthening for Accurate, Complete and Robust Vessel Segmentationcited by 3
- 2023MEMO: Dataset and Methods for Robust Multimodal Retinal Image Registration with Large or Small Vessel Density Differencescited by 3
- 2025Universal Vessel Segmentation for Multi-Modality Retinal Imagescited by 3
- 2021Dive into Layers: Neural Network Capacity Bounding using Algebraic Geometrycited by 2
- 2021Optic Disc Segmentation using Disk-Centered Patch Augmentationcited by 2
- 2022Weakly-supervised detection of AMD-related lesions in color fundus images using explainable deep learningcited by 2
- 2023SCOPE: Structural Continuity Preservation for Medical Image Segmentationcited by 2
- 2024Retinal Vessel Segmentation with Deep Graph and Capsule Reasoningcited by 2
- 2025CAPE: Connectivity-Aware Path Enforcement Loss for Curvilinear Structure Delineationcited by 2
- 2021A Deep Learning-Based Unified Framework for Red Lesions Detection on Retinal Fundus Imagescited by 1
- 2021Adjusting the Ground Truth Annotations for Connectivity-Based Learning to Delineatecited by 1
- 2023Robust Unsupervised Domain Adaptation by Retaining Confident Entropy via Edge Concatenationcited by 1
- 2021Automated airway segmentation by learning graphical structurecited by 0
- 2022A Graphical Approach For Brain Haemorrhage Segmentationcited by 0
- 2022A comprehensive survey on computer-aided diagnostic systems in diabetic retinopathy screeningcited by 0
- 2022Introduction to Machine Learning for Physicians: A Survival Guide for Data Delugecited by 0
- 2024TransResNet: Integrating the Strengths of ViTs and CNNs for High Resolution Medical Image Segmentation via Feature Graftingcited by 0
- 2024TransUNext: towards a more advanced U-shaped framework for automatic vessel segmentation in the fundus imagecited by 0
- 2025A Deep Convolutional Neural Network-Based Novel Class Balancing for Imbalance Data Segmentationcited by 0
- 2026D-Convexity: A Unified Differentiable Convex Shape Prior via Quasi-Concavity for Data-driven Image Segmentationcited by 0
- 2026Observer Choice and Threshold Selection in Retinal Vessel Segmentation: A Subject-Separated Evaluationcited by 0
- 2026Observer Choice and Threshold Selection in Retinal Vessel Segmentation: A Subject-Separated Evaluation22 Sep 2026
- 2026D-Convexity: A Unified Differentiable Convex Shape Prior via Quasi-Concavity for Data-driven Image Segmentation19 May 2026
- 2025A Deep Convolutional Neural Network-Based Novel Class Balancing for Imbalance Data Segmentation23 Jun 2025
- 2025CAPE: Connectivity-Aware Path Enforcement Loss for Curvilinear Structure Delineation1 Apr 2025
- 2025Universal Vessel Segmentation for Multi-Modality Retinal Images10 Feb 2025
- 2024TransUNext: towards a more advanced U-shaped framework for automatic vessel segmentation in the fundus image5 Nov 2024
- 2024TransResNet: Integrating the Strengths of ViTs and CNNs for High Resolution Medical Image Segmentation via Feature Grafting1 Oct 2024
- 2024Retinal Vessel Segmentation with Deep Graph and Capsule Reasoning17 Sep 2024
- 2024Advancing Medical Image Segmentation with Mini-Net: A Lightweight Solution Tailored for Efficient Segmentation of Medical Images27 May 2024
- 2023ESDMR-Net: A Lightweight Network With Expand-Squeeze and Dual Multiscale Residual Connections for Medical Image Segmentation17 Dec 2023
- 2023Robust Unsupervised Domain Adaptation by Retaining Confident Entropy via Edge Concatenation11 Oct 2023
- 2023MEMO: Dataset and Methods for Robust Multimodal Retinal Image Registration with Large or Small Vessel Density Differences25 Sep 2023
23 more
- 2023Feature Enhancer Segmentation Network (FES-Net) for Vessel Segmentation7 Sep 2023
- 2023SCOPE: Structural Continuity Preservation for Medical Image Segmentation28 Apr 2023
- 2022Introduction to Machine Learning for Physicians: A Survival Guide for Data Deluge23 Dec 2022
- 2022Weakly-supervised detection of AMD-related lesions in color fundus images using explainable deep learning1 Dec 2022
- 2022Affinity Feature Strengthening for Accurate, Complete and Robust Vessel Segmentation12 Nov 2022
- 2022MKIS-Net: A Light-Weight Multi-Kernel Network for Medical Image Segmentation15 Oct 2022
- 2022A comprehensive survey on computer-aided diagnostic systems in diabetic retinopathy screening3 Aug 2022
- 2022AADG: Automatic Augmentation for Domain Generalization on Retinal Image Segmentation27 Jul 2022
- 2022Orientation and Context Entangled Network for Retinal Vessel Segmentation23 Jul 2022
- 2022Enforcing connectivity of 3D linear structures using their 2D projections14 Jul 2022
- 2022Local Intensity Order Transformation for Robust Curvilinear Object Segmentation25 Feb 2022
- 2022A Graphical Approach For Brain Haemorrhage Segmentation14 Feb 2022
- 2021RC-Net: A Convolutional Neural Network for Retinal Vessel Segmentation21 Dec 2021
- 2021Adjusting the Ground Truth Annotations for Connectivity-Based Learning to Delineate6 Dec 2021
- 2021An Analysis of the Influence of Transfer Learning When Measuring the Tortuosity of Blood Vessels19 Nov 2021
- 2021DR-VNet: Retinal Vessel Segmentation via Dense Residual UNet8 Nov 2021
- 2021Optic Disc Segmentation using Disk-Centered Patch Augmentation1 Oct 2021
- 2021Automated airway segmentation by learning graphical structure30 Sep 2021
- 2021A Deep Learning-Based Unified Framework for Red Lesions Detection on Retinal Fundus Images10 Sep 2021
- 2021Dive into Layers: Neural Network Capacity Bounding using Algebraic Geometry3 Sep 2021
- 2021Uncertainty guided semi-supervised segmentation of retinal layers in OCT images2 Mar 2021
- 2021Sequential vessel segmentation via deep channel attention network10 Feb 2021
- 2021Applications of Deep Learning in Fundus Images: A Review25 Jan 2021
- 2021Applications of Deep Learning in Fundus Images: A Reviewcited by 59
- 2021Uncertainty guided semi-supervised segmentation of retinal layers in OCT imagescited by 29
- 2022AADG: Automatic Augmentation for Domain Generalization on Retinal Image Segmentationcited by 18
- 2021Sequential vessel segmentation via deep channel attention networkcited by 14
- 2022MKIS-Net: A Light-Weight Multi-Kernel Network for Medical Image Segmentationcited by 13
- 2021RC-Net: A Convolutional Neural Network for Retinal Vessel Segmentationcited by 12
- 2022Local Intensity Order Transformation for Robust Curvilinear Object Segmentationcited by 12
- 2023Feature Enhancer Segmentation Network (FES-Net) for Vessel Segmentationcited by 10
- 2023ESDMR-Net: A Lightweight Network With Expand-Squeeze and Dual Multiscale Residual Connections for Medical Image Segmentationcited by 9
- 2024Advancing Medical Image Segmentation with Mini-Net: A Lightweight Solution Tailored for Efficient Segmentation of Medical Imagescited by 9
- 2022Orientation and Context Entangled Network for Retinal Vessel Segmentationcited by 8
- 2021DR-VNet: Retinal Vessel Segmentation via Dense Residual UNetcited by 6
12 most cited of 35 All 35 (JSON)
- 2026Observer Choice and Threshold Selection in Retinal Vessel Segmentation: A Subject-Separated Evaluation22 Sep 2026
- 2026D-Convexity: A Unified Differentiable Convex Shape Prior via Quasi-Concavity for Data-driven Image Segmentation19 May 2026
- 2025A Deep Convolutional Neural Network-Based Novel Class Balancing for Imbalance Data Segmentation23 Jun 2025
- 2025CAPE: Connectivity-Aware Path Enforcement Loss for Curvilinear Structure Delineation1 Apr 2025
- 2025Universal Vessel Segmentation for Multi-Modality Retinal Images10 Feb 2025
- 2024TransUNext: towards a more advanced U-shaped framework for automatic vessel segmentation in the fundus image5 Nov 2024
- 2024TransResNet: Integrating the Strengths of ViTs and CNNs for High Resolution Medical Image Segmentation via Feature Grafting1 Oct 2024
- 2024Retinal Vessel Segmentation with Deep Graph and Capsule Reasoning17 Sep 2024
- 2024Advancing Medical Image Segmentation with Mini-Net: A Lightweight Solution Tailored for Efficient Segmentation of Medical Images27 May 2024
- 2023ESDMR-Net: A Lightweight Network With Expand-Squeeze and Dual Multiscale Residual Connections for Medical Image Segmentation17 Dec 2023
- 2023Robust Unsupervised Domain Adaptation by Retaining Confident Entropy via Edge Concatenation11 Oct 2023
- 2023MEMO: Dataset and Methods for Robust Multimodal Retinal Image Registration with Large or Small Vessel Density Differences25 Sep 2023
12 newest of 35 All 35 (JSON)