Scalable Interpretable Multi-Response Regression via SEED

Sparse reduced-rank regression is an important tool to uncover meaningful dependence structure between large numbers of predictors and responses in many big data applications such as genome-wide association studies and social media analysis. Despite the recent theoretical and algorithmic advances, scalable estimation of sparse reduced-rank regression remains largely unexplored. In this paper, we suggest a scalable procedure called sequential estimation with eigen-decomposition (SEED) which needs only a single top-r singular value decomposition to find the optimal low-rank and sparse matrix by solving a sparse generalized eigenvalue problem. Our suggested method is not only scalable but also performs simultaneous dimensionality reduction and variable selection. Under some mild regularity conditions, we show that SEED enjoys nice sampling properties including consistency in estimation, rank selection, prediction, and model selection. Numerical studies on synthetic and real data sets show that SEED outperforms the state-of-the-art approaches for large-scale matrix estimation problem.