# Mixed Poisson diffusion models and application to posterior sampling

arXiv: https://arxiv.org/abs/2610.20218 · HTML: https://mlsanity.com/paper/2610.20218/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Diffusion foundations and sampling, one of 14 directions in Diffusion models.
- Builds on 17 of its 32 references that are in the map.
- First posted on arXiv 14 Oct 2026.

## Placed in

- Diffusion models / [Diffusion foundations and sampling](https://mlsanity.com/diffusion/diffusion-foundations-and-sampling/)

## Builds on (most cited first, 17 of 17)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [Structured Denoising Diffusion Models in Discrete State-Spaces](https://mlsanity.com/paper/2107.03006/) (2021)
- [Diffusion Posterior Sampling for General Noisy Inverse Problems](https://mlsanity.com/paper/2209.14687/) (2022)
- [Denoising Diffusion Restoration Models](https://mlsanity.com/paper/2201.11793/) (2022)
- [A Continuous Time Framework for Discrete Denoising Models](https://mlsanity.com/paper/2205.14987/) (2022)
- [Improving Diffusion Inverse Problem Solving with Decoupled Noise Annealing](https://mlsanity.com/paper/2407.01521/) (2024)
- [Principled Probabilistic Imaging using Diffusion Models as Plug-and-Play Priors](https://mlsanity.com/paper/2405.18782/) (2024)
- [Information-Theoretic Diffusion](https://mlsanity.com/paper/2302.03792/) (2023)
- [Sampling, Diffusions, and Stochastic Localization](https://mlsanity.com/paper/2305.10690/) (2023)
- [Stochastic Localization via Iterative Posterior Sampling](https://mlsanity.com/paper/2402.10758/) (2024)
- [Learning to Jump: Thinning and Thickening Latent Counts for Generative Modeling](https://mlsanity.com/paper/2305.18375/) (2023)
- [A Mixture-Based Framework for Guiding Diffusion Models](https://mlsanity.com/paper/2502.03332/) (2025)
- [Chain of Log-Concave Markov Chains](https://mlsanity.com/paper/2305.19473/) (2023)
- [ItDPDM: Information-Theoretic Discrete Poisson Diffusion Model](https://mlsanity.com/paper/2505.05082/) (2025)

## Abstract (arXiv)

Diffusion models are a powerful framework for learning complex probability distributions. While widely used diffusion models for continuous data rely on Gaussian noising processes, we instead develop diffusion models based on Poisson noise. More precisely, we introduce and study a new mathematical framework, called Mixed Poisson Diffusion Models (MPDM), with noising dynamics driven by multivariate counting processes. Our methodology is motivated by Poisson inverse problems. The success of Gaussian diffusion models has led to their use as prior models in a growing number of posterior sampling methods for inverse problems. However, most of these approaches focus on Gaussian inverse problems, in which observations are generated through a deterministic forward operator corrupted by additive Gaussian noise. By contrast, Poisson inverse problems, where observations are discrete and Poisson distributed, remain comparatively underexplored in this literature. Building on our Poisson generative dynamics, we develop a natural framework for posterior sampling in Poisson inverse problems and derive several posterior sampling algorithms based on the proposed model. We evaluate our approach on realistic Poisson inverse problems and show that the resulting framework is well suited to this class of problems.